Autoimmune hepatitis associated Hepatitis C virus infection treated with fi rst generation direct-acting antivirals
<p>The hepatitis C virus (HCV) infection has been associated with autoimmune diseases, probably due to the interaction between HCV E2 envelope protein and CD-81 receptor of B lymphocyte and thus, can infl uence the pathogenesis of autoimmune liver diseases [1,2]. Therefore, it seems reasonable...
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Annals of Antivirals and Antiretrovirals - Peertechz Publications,
2019-10-04.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_aaa_000006 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Juan Diego Castro Limo |e author |
| 700 | 1 | 0 | |a Tomas Artaza Varasa |e author |
| 700 | 1 | 0 | |a Maria Recuero Pradillo |e author |
| 700 | 1 | 0 | |a Marta Romero-Gutierrez |e author |
| 700 | 1 | 0 | |a Ana Zaida Gomez Moreno |e author |
| 700 | 1 | 0 | |a Juan Jose Sanchez Ruano |e author |
| 700 | 1 | 0 | |a Carlos San Roman Gutierrez |e author |
| 700 | 1 | 0 | |a Pablo Munoz Gomez |e author |
| 700 | 1 | 0 | |a Rafael Gomez Rodríguez |e author |
| 245 | 0 | 0 | |a Autoimmune hepatitis associated Hepatitis C virus infection treated with fi rst generation direct-acting antivirals |
| 260 | |b Annals of Antivirals and Antiretrovirals - Peertechz Publications, |c 2019-10-04. | ||
| 520 | |a <p>The hepatitis C virus (HCV) infection has been associated with autoimmune diseases, probably due to the interaction between HCV E2 envelope protein and CD-81 receptor of B lymphocyte and thus, can infl uence the pathogenesis of autoimmune liver diseases [1,2]. Therefore, it seems reasonable to consider the benefi cial effect of direct-acting antivirals (DAAs) for HCV in patients with chronic HCV infection and autoimmune hepatitis (HAI), although evidence is scarce. We report the case of an HCV-infected patient who developed an HAI triggered by interferon and since then has been treated with DAAs improving liver function and maintaining sustained virologic response (SVR), without immunosuppressive treatment nowadays.</p> | ||
| 540 | |a Copyright © Juan Diego Castro Limo et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Case Report |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/aaa.000006 |z Connect to this object online. |