Bromelain: A potential therapeutic application in SARS-CoV-2 infected patients

• Main Authors: Serkan Sayıner (Author), Ayliz Velioğlu-Öğünç (Author), Ahmet Özer Şehirli (Author)
• Format: Book
• Published: Annals of Antivirals and Antiretrovirals - Peertechz Publications, 2021-06-19.
• Subjects: Mini Review
• Online Access: Connect to this object online.

<p>The SARS-CoV-2 infection has led to a global pandemic which has led to almost 4 million deaths worldwide. However, to date, a specific antiviral drug does not exist to treat the disease and control the virus. Here, we focus on the potential use of bromelain in line with its anti-oxidant, anti-inflammatory, and immunomodulatory effects. Additionally, bromelain exerts fibrinolytic, anti-invasive and antithrombotic activities that may become a therapeutic candidate against SARS-CoV-2 infection. In this paper, we focused on bromelain's therapeutic potential concerning its potential role in reducing the severity of symptoms and the adverse effects of other antiviral drugs currently being used. The therapeutic effects of bromelain suggests that it may reduce mortality and morbidity rates in patients with CoVID-19 infections, through its anti-oxidant, anti-inflammatory, immunomodulator and anticoagulant effects. These positive effects leads us to propose that bromelain may be clinically valuable in the treatment of COVID-19 and that it therapeutic attributes should be fully investigated.</p>