Microwave Irradiated and Conventional Synthesis, Antibacterial Activity Evaluation Studies of Tryptamine-Azole-Fluoroquinolone Conjugates

<p>Tryptamine was converted to the corresponding 1,2,4-triazole, 1,3,4-oxadiazole, 5-oxo-1,3-thia(oxa)zolidine and 5-(4-chlorophenyl)-1,3-thia(oxa)zole derivatives via several steps. 1,3,4-oxadiazole and 1,2,4-triazoles were then converted to the corresponding Mannich bases containing fluroqui...

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Detaylı Bibliyografya
Asıl Yazarlar: Yıldız Uygun Cebeci1 (Yazar), Serap Basoglu Özdemir1 (Yazar), Ahmet Demirbas1 (Yazar), Neslihan Demirbas (Yazar), Sengül Alpay Karaoglu (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Archive of Biomedical Science and Engineering - Peertechz Publications, 2018-12-21.
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042 |a dc 
100 1 0 |a Yıldız Uygun Cebeci1  |e author 
700 1 0 |a  Serap Basoglu Özdemir1  |e author 
700 1 0 |a  Ahmet Demirbas1  |e author 
700 1 0 |a  Neslihan Demirbas  |e author 
700 1 0 |a Sengül Alpay Karaoglu  |e author 
245 0 0 |a Microwave Irradiated and Conventional Synthesis, Antibacterial Activity Evaluation Studies of Tryptamine-Azole-Fluoroquinolone Conjugates 
260 |b Archive of Biomedical Science and Engineering - Peertechz Publications,   |c 2018-12-21. 
520 |a <p>Tryptamine was converted to the corresponding 1,2,4-triazole, 1,3,4-oxadiazole, 5-oxo-1,3-thia(oxa)zolidine and 5-(4-chlorophenyl)-1,3-thia(oxa)zole derivatives via several steps. 1,3,4-oxadiazole and 1,2,4-triazoles were then converted to the corresponding Mannich bases containing fluroquinolone core using a one-pot three-components procedure. Conventional and microwave-assisted methods were applied for all syntheses. All the newly synthesized compounds were screened for their antibacterial and most of them were found to have good-moderate antibacterial activity.</p> 
540 |a Copyright © Yıldız Uygun Cebeci1 et al. 
546 |a en 
655 7 |a Research Article  |2 local 
856 4 1 |u https://doi.org/10.17352/abse.000009  |z Connect to this object online.