Microwave Irradiated and Conventional Synthesis, Antibacterial Activity Evaluation Studies of Tryptamine-Azole-Fluoroquinolone Conjugates
<p>Tryptamine was converted to the corresponding 1,2,4-triazole, 1,3,4-oxadiazole, 5-oxo-1,3-thia(oxa)zolidine and 5-(4-chlorophenyl)-1,3-thia(oxa)zole derivatives via several steps. 1,3,4-oxadiazole and 1,2,4-triazoles were then converted to the corresponding Mannich bases containing fluroqui...
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Archive of Biomedical Science and Engineering - Peertechz Publications,
2018-12-21.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_abse_000009 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Yıldız Uygun Cebeci1 |e author |
| 700 | 1 | 0 | |a Serap Basoglu Özdemir1 |e author |
| 700 | 1 | 0 | |a Ahmet Demirbas1 |e author |
| 700 | 1 | 0 | |a Neslihan Demirbas |e author |
| 700 | 1 | 0 | |a Sengül Alpay Karaoglu |e author |
| 245 | 0 | 0 | |a Microwave Irradiated and Conventional Synthesis, Antibacterial Activity Evaluation Studies of Tryptamine-Azole-Fluoroquinolone Conjugates |
| 260 | |b Archive of Biomedical Science and Engineering - Peertechz Publications, |c 2018-12-21. | ||
| 520 | |a <p>Tryptamine was converted to the corresponding 1,2,4-triazole, 1,3,4-oxadiazole, 5-oxo-1,3-thia(oxa)zolidine and 5-(4-chlorophenyl)-1,3-thia(oxa)zole derivatives via several steps. 1,3,4-oxadiazole and 1,2,4-triazoles were then converted to the corresponding Mannich bases containing fluroquinolone core using a one-pot three-components procedure. Conventional and microwave-assisted methods were applied for all syntheses. All the newly synthesized compounds were screened for their antibacterial and most of them were found to have good-moderate antibacterial activity.</p> | ||
| 540 | |a Copyright © Yıldız Uygun Cebeci1 et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Research Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/abse.000009 |z Connect to this object online. |