Fever Induced Brugada Syndrome
<p>Brugada syndrome is a heterogeneous genetic channelopathy that predisposes to ventricular arrhythmias and sudden cardiac death (SCD). The electrocardiogram (ECG) findings only suggest a diagnosis of Brugada syndrome but are not confirmatory. The ECG pattern is known to vary with time in som...
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Annals of Circulation - Peertechz Publications,
2017-07-03.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_ac_000008 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Aditya A Munshi |e author |
245 | 0 | 0 | |a Fever Induced Brugada Syndrome |
260 | |b Annals of Circulation - Peertechz Publications, |c 2017-07-03. | ||
520 | |a <p>Brugada syndrome is a heterogeneous genetic channelopathy that predisposes to ventricular arrhythmias and sudden cardiac death (SCD). The electrocardiogram (ECG) findings only suggest a diagnosis of Brugada syndrome but are not confirmatory. The ECG pattern is known to vary with time in some patients and many have a normal baseline ECG [1,2]. There are two distinctly described ECG patterns, type I Brugada is characterized by ST elevation (≥2mm) with a "coved" pattern or a T-wave which is inverted with an upward convexity, in other cases the elevated ST segment descends and rises again forming a "saddleback" type pattern, this is called the type II Brugada. The electrophysiological and clinical manifestations of this syndrome have been found to be secondary to various factors [3-10]. Of these, mutations in cardiac sodium channel SCN genes (SCN5A and SCN10A) are the most well-known [11]. Since all affected families do not have these mutations, it is believed that other mutations in sodium channel genes or mutations in non-sodium channel genes may also cause Brugada syndrome [12-15].</p> | ||
540 | |a Copyright © Aditya A Munshi et al. | ||
546 | |a en | ||
655 | 7 | |a Letter to Editor |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/ac.000008 |z Connect to this object online. |