Coupled blood pressure dynamics in magisterial and small arteries networks and its stabilizing effect on heart functioning within the framework of computer model

• Main Authors: Alexander Shmid (Author), Novopashin MA (Author), Andrey Berezin (Author)
• Format: Book
• Published: Annals of Circulation - Peertechz Publications, 2018-02-22.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Computer model coupled blood pressure dynamics in magisterial and small arteries networks and its stabilizing effect on heart functioning has been suggested. The Fermi-Pasta-Ulam auto recurrence in the description of the electrical activity of the heart has demonstrated the universal role of the FPU recurrence in the study of distributed dynamical systems. The heart electrical dynamics was described by the coupled Van der Pol differential equations with a time lag, linked with two additively coupled nonlinear differential equations circumscribing the blood pressure dynamics in the networks of magisterial and small arteries. The mathematical model developed by Yuen and Lake for description of the deep wave dynamics within the nonlinear Shrodinger (NSE) equation was used for description of the magisterial arterial blood pressure whereas for small arteries blood pressure dynamics was used the approach elaborated by Zabusky and Kruskal within the framework of the Korteveg de Vries (KdV) equation. The arterial blood pressure dynamics was interpreted as coupled FPU recurrences showing a rich variety of resulting FPU spectra, which were referred to different states of Cardio Vascular System. Synchronous registering of the real ECG and Pulse Wave Fourier dynamic images allowed to unify the characteristic Fourier pictures of the heart electrical activity with the hydrodynamic blood parameters developing in the networks of two types of arteries. The computer study of the suggested model and comparison of its results with the real data proved that the ECG Fourier parameters coupled with the Pulse Wave Fourier parameters form the FPU spectra that increase stability of Cardio Vascular System and can be used for diagnostics as well as for evaluation of the therapeutic arrangements results.</p>