Usefullness of Phytoestrogens in Treatment of Arterial Hypertension. Systematic Review and Meta-Analysis: Un Update

• Main Authors: Garcia Garcia MA (Author), Rosero Arenas MA (Author), Martinez Cornejo A (Author), Perez Lluna L (Author)
• Format: Book
• Published: Archives of Clinical Hypertension - Peertechz Publications, 2016-04-12.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p><strong>Background</strong>: It has been suggested that phytoestrogens may have utility in the control of arterial hypertension. <br></p><p><strong>Methods</strong>: We performed a systematic review and meta-analysis of randomized controlled trials, and the main outcome was the decrease of blood pressure.</p><p><strong>Results:</strong> Decrease in systolic (- 0,15 mmHg, CI 95% from -0,24 to -0,05) and diastolic (-0,14 mmHg, CI 95% from -0,25 to -0,03) blood pressure were observed in patients taking phytoestrogens, but this difference was not clinically relevant. There can be a little greater decrease in Asian patients and in patients with higher baseline blood pressure values.</p><p><strong>Conclusion:</strong> The global effect of phytoestrogens seems of small amount in reducing blood pressure. Nevertheless, it has not been realized a clinical trials about the efficacy of these products in no mild hypertensive patients, similar to real life.</p>