Acute Renal Failure in Sarcoidosis: A Review of the Literature

<p>We report two cases of acute kidney failure (ARF) as the initial manifestation of sarcoidosis. Two patients were sent from their primary care physicians with hypercalcemia and progressive increase of serum creatinine. The renal biopsy revealed granulomatous interstitial nephritis (GIN). Bot...

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Главные авторы: Teresa Papalia (Автор), Rosita Greco (Автор), Agata Mollica (Автор), Renzo Bonofiglio (Автор)
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Опубликовано: Archives of Clinical Nephrology - Peertechz Publications, 2016-04-26.
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042 |a dc 
100 1 0 |a Teresa Papalia  |e author 
700 1 0 |a  Rosita Greco  |e author 
700 1 0 |a  Agata Mollica  |e author 
700 1 0 |a Renzo Bonofiglio  |e author 
245 0 0 |a Acute Renal Failure in Sarcoidosis: A Review of the Literature 
260 |b Archives of Clinical Nephrology - Peertechz Publications,   |c 2016-04-26. 
520 |a <p>We report two cases of acute kidney failure (ARF) as the initial manifestation of sarcoidosis. Two patients were sent from their primary care physicians with hypercalcemia and progressive increase of serum creatinine. The renal biopsy revealed granulomatous interstitial nephritis (GIN). Both patients were started on Methylprednisolone pulse therapy, followed by administration of oral prednisolone and by a slow taper thereafter to a maintenance dose. The renal function has improved immediately in response to this therapy. Our cases demostrates thet GIN due to sarcoidosis, although a rare entity, can cause severe ARF and progressive ESRD. With early detection and appropriate therapy, the majority of patients will maintain adequate renal function. Therefore the diagnosis of renal sarcoidosis must be done quickly to prevent renal.</p> 
540 |a Copyright © Teresa Papalia et al. 
546 |a en 
655 7 |a Review Article  |2 local 
856 4 1 |u https://doi.org/10.17352/acn.000008  |z Connect to this object online.