Antiphosphlipid Syndrome Presented with Renovascular Hypertension

<p>Renovascular pathologies are one of the treatable causes of hypertension. Antiphospholipid syndrome develops owing to a heterogeneous group of antiphospholipid antibodies which causes various thrombotic problems. This entity may effects very small vessels and sometimes leads to hypertension...

Full description

Saved in:
Bibliographic Details
Main Authors: Savas Ozturk (Author), Mukremin Uysal (Author), Fulya Cosan (Author), Banu Buyukaydin (Author), Murat Inanc (Author), Reyhan Diz-Kucukkaya (Author), Isın Kılıcarslan (Author), Aydin Turkmen (Author), Rumeyza Kazancioglu (Author)
Format: Book
Published: Archives of Clinical Nephrology - Peertechz Publications, 2016-06-16.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:<p>Renovascular pathologies are one of the treatable causes of hypertension. Antiphospholipid syndrome develops owing to a heterogeneous group of antiphospholipid antibodies which causes various thrombotic problems. This entity may effects very small vessels and sometimes leads to hypertension. We present a 55-year-old female with unilateral renal artery stent implantation because of renovascular hypertension. After application, a re-stenosis developed and in-stent angioplasty was performed, but it was required a nephrectomy because of haemorrhage. Severe ischemic nephropathy was detected in the nephrectomy material. She was diagnosed with antiphospholipid syndrome. Prolonged prothrombin time with hemorrhagic diathesis which coexisting thrombosis responded steroid therapy. But in follow-up, the thrombocytopenia developed, the patient could not recieve anticoagulant therapy and died due to a pulmonary embolism-like syndrome. This case reminds, renovascular hypertension is one of the major reasons of secondary hypertension and antiphospholipid syndrome always should be considered in thrombotic processes.</p>
DOI:10.17352/acn.000010