Immune thrombocytopenic purpura with subsequent development of JAK2 V617F-positive essential thrombocythemia: Case Report
<p>The sequential occurrence of Immune Thrombocytopenic Purpura (ITP) and Essential Thrombocythemia (ET) has been reported in the literature on a few occasions, as these are two hematologic disorders with distinct etiologies and patients usually have contrasting clinical presentations. Our cas...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Published: |
Archives of Hematology Case Reports and Reviews - Peertechz Publications,
2021-08-04.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_ahcrr_000033 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Marisabel Hurtado-Castillo |e author |
| 700 | 1 | 0 | |a Brian Flaherty |e author |
| 700 | 1 | 0 | |a Morris Jrada |e author |
| 245 | 0 | 0 | |a Immune thrombocytopenic purpura with subsequent development of JAK2 V617F-positive essential thrombocythemia: Case Report |
| 260 | |b Archives of Hematology Case Reports and Reviews - Peertechz Publications, |c 2021-08-04. | ||
| 520 | |a <p>The sequential occurrence of Immune Thrombocytopenic Purpura (ITP) and Essential Thrombocythemia (ET) has been reported in the literature on a few occasions, as these are two hematologic disorders with distinct etiologies and patients usually have contrasting clinical presentations. Our case highlights the sequential occurrence of ITP, followed by Janus kinase 2 (JAK2) (V617F)-positive ET in a 64-year-old white woman, after four years of follow-up. The pathophysiology relating to these two conditions is incompletely understood, however, JAK2(V617F) mutation has been found in all the cases reported. Early identification of JAK2(V617F) mutation in a patient with a past medical history of ITP and presenting with thrombocytosis, may lead to a prompt diagnosis of ET and timely treatment initiation.</p> | ||
| 540 | |a Copyright © Marisabel Hurtado-Castillo et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Case Report |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/ahcrr.000033 |z Connect to this object online. |