Immune thrombocytopenic purpura with subsequent development of JAK2 V617F-positive essential thrombocythemia: Case Report

<p>The sequential occurrence of Immune Thrombocytopenic Purpura (ITP) and Essential Thrombocythemia (ET) has been reported in the literature on a few occasions, as these are two hematologic disorders with distinct etiologies and patients usually have contrasting clinical presentations. Our cas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Marisabel Hurtado-Castillo (Tekijä), Brian Flaherty (Tekijä), Morris Jrada (Tekijä)
Aineistotyyppi: Kirja
Julkaistu: Archives of Hematology Case Reports and Reviews - Peertechz Publications, 2021-08-04.
Aiheet:
Linkit:Connect to this object online.
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

MARC

LEADER 00000 am a22000003u 4500
001 peertech__10_17352_ahcrr_000033
042 |a dc 
100 1 0 |a Marisabel Hurtado-Castillo  |e author 
700 1 0 |a  Brian Flaherty  |e author 
700 1 0 |a Morris Jrada  |e author 
245 0 0 |a Immune thrombocytopenic purpura with subsequent development of JAK2 V617F-positive essential thrombocythemia: Case Report 
260 |b Archives of Hematology Case Reports and Reviews - Peertechz Publications,   |c 2021-08-04. 
520 |a <p>The sequential occurrence of Immune Thrombocytopenic Purpura (ITP) and Essential Thrombocythemia (ET) has been reported in the literature on a few occasions, as these are two hematologic disorders with distinct etiologies and patients usually have contrasting clinical presentations. Our case highlights the sequential occurrence of ITP, followed by Janus kinase 2 (JAK2) (V617F)-positive ET in a 64-year-old white woman, after four years of follow-up. The pathophysiology relating to these two conditions is incompletely understood, however, JAK2(V617F) mutation has been found in all the cases reported. Early identification of JAK2(V617F) mutation in a patient with a past medical history of ITP and presenting with thrombocytosis, may lead to a prompt diagnosis of ET and timely treatment initiation.</p> 
540 |a Copyright © Marisabel Hurtado-Castillo et al. 
546 |a en 
655 7 |a Case Report  |2 local 
856 4 1 |u https://doi.org/10.17352/ahcrr.000033  |z Connect to this object online.