Immune thrombocytopenic purpura with subsequent development of JAK2 V617F-positive essential thrombocythemia: Case Report
<p>The sequential occurrence of Immune Thrombocytopenic Purpura (ITP) and Essential Thrombocythemia (ET) has been reported in the literature on a few occasions, as these are two hematologic disorders with distinct etiologies and patients usually have contrasting clinical presentations. Our cas...
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Archives of Hematology Case Reports and Reviews - Peertechz Publications,
2021-08-04.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_ahcrr_000033 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Marisabel Hurtado-Castillo |e author |
700 | 1 | 0 | |a Brian Flaherty |e author |
700 | 1 | 0 | |a Morris Jrada |e author |
245 | 0 | 0 | |a Immune thrombocytopenic purpura with subsequent development of JAK2 V617F-positive essential thrombocythemia: Case Report |
260 | |b Archives of Hematology Case Reports and Reviews - Peertechz Publications, |c 2021-08-04. | ||
520 | |a <p>The sequential occurrence of Immune Thrombocytopenic Purpura (ITP) and Essential Thrombocythemia (ET) has been reported in the literature on a few occasions, as these are two hematologic disorders with distinct etiologies and patients usually have contrasting clinical presentations. Our case highlights the sequential occurrence of ITP, followed by Janus kinase 2 (JAK2) (V617F)-positive ET in a 64-year-old white woman, after four years of follow-up. The pathophysiology relating to these two conditions is incompletely understood, however, JAK2(V617F) mutation has been found in all the cases reported. Early identification of JAK2(V617F) mutation in a patient with a past medical history of ITP and presenting with thrombocytosis, may lead to a prompt diagnosis of ET and timely treatment initiation.</p> | ||
540 | |a Copyright © Marisabel Hurtado-Castillo et al. | ||
546 | |a en | ||
655 | 7 | |a Case Report |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/ahcrr.000033 |z Connect to this object online. |