Combined treatment with vemurafenib and cobimetinib in Langerhans cell histiocytosis and Erdheim-Chester disease overlap syndrome: A case Report

• Main Authors: Hidalgo-Soto Marta (Author), Poza-Santaella María (Author), Pita-Suárez Daniel (Author), Calbacho-Robles María (Author), Pina-Sánchez José (Author), González-Medina José (Author), Baumann Tycho Stephan (Author)
• Format: Book
• Published: Archives of Hematology Case Reports and Reviews - Peertechz Publications, 2022-01-20.
• Subjects: Case Report
• Online Access: Connect to this object online.

<p>Histiocytoses are clonal disorders diseases derived from the monocyte-macrophage lineage. The Erdheim-Chester Disease (ECD) and Langerhans Cell Histiocytosis (LCH) may occur in association with overlapping clinical, histopathological and molecular features, harboring somatic MAP2K1 mutation...