Occult Hepatitis B Virus infection in a cohort of patients with chronic Hepatitis C

<p><strong>Introduction</strong>: The prevalence of occult hepatitis B, defi ned by absence of HBsAg and HBV DNA, ranges widely in patients with hepatitis C. This may infl uence the treatment of hepatitis C and the severity of liver disease</p><p><strong>Aim of wo...

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Main Authors: MI Naga (Author), MA Amin (Author), DA Algendy (Author), AI El Badry (Author), MM Fawzi (Author), AR Foda (Author), SM Esmat (Author), SM Gabal (Author), D Sabry (Author), M Kamal (Author), LA Rashed (Author)
Format: Book
Published: Archives of Hepatitis Research - Peertechz Publications, 2019-07-26.
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Summary:<p><strong>Introduction</strong>: The prevalence of occult hepatitis B, defi ned by absence of HBsAg and HBV DNA, ranges widely in patients with hepatitis C. This may infl uence the treatment of hepatitis C and the severity of liver disease</p><p><strong>Aim of work and methods</strong>: Was to determine the prevalence of occult hepatitis B virus infection and liver of HBsAg negative patients with chronic hepatitis C and to evaluate its clinical consequences on liver pathology and its impact on the response to treatment with peg-IFNa and Ribavirin. Immunohistochemistry staining for hepatitis B surface antigen and HBV DNA detection was assessed retrospectively on liver biopsies of HCV positive/ HBsAg negative patients before treatment.</p>
DOI:10.17352/ahr.000022