Nutritional intervention for cancer sarcopenia
<p>Most patients with advanced cancer develop skeletal muscle atrophy called sarcopenia, which reduces treatment tolerance and social activity and worsens the prognosis. Glucose suppresses skeletal muscle atrophy in cancer-bearing mice, while promoting cancer growth. In contrast, medium-chain...
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Annals of Musculoskeletal Medicine - Peertechz Publications,
2021-01-06.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_amm_000024 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Takuya Mori |e author |
700 | 1 | 0 | |a Akira Kido |e author |
700 | 1 | 0 | |a Isao Kawahara |e author |
700 | 1 | 0 | |a Shota Nuaga |e author |
700 | 1 | 0 | |a Yoshihiro Miyagawa |e author |
700 | 1 | 0 | |a Kei Goto |e author |
700 | 1 | 0 | |a Shiori Mori |e author |
700 | 1 | 0 | |a Shingo Kishi |e author |
700 | 1 | 0 | |a Kiyomu Fujii |e author |
700 | 1 | 0 | |a Rina Fujiwara-Tani |e author |
700 | 1 | 0 | |a Hiroki Kuniyasu |e author |
245 | 0 | 0 | |a Nutritional intervention for cancer sarcopenia |
260 | |b Annals of Musculoskeletal Medicine - Peertechz Publications, |c 2021-01-06. | ||
520 | |a <p>Most patients with advanced cancer develop skeletal muscle atrophy called sarcopenia, which reduces treatment tolerance and social activity and worsens the prognosis. Glucose suppresses skeletal muscle atrophy in cancer-bearing mice, while promoting cancer growth. In contrast, medium-chain fatty acids reduce skeletal muscle atrophy and suppress cancer growth. Simultaneous administration of glucose and medium-chain fatty acids suppresses skeletal muscle atrophy and eliminates the tumor growth seen in glucose. Based on these findings, dietary intervention using a combination of glucose and medium-chain fatty acids is expected to be effective in suppressing sarcopenia in cancer patients.</p> | ||
540 | |a Copyright © Takuya Mori et al. | ||
546 | |a en | ||
655 | 7 | |a Research Article |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/amm.000024 |z Connect to this object online. |