Nutritional intervention for cancer sarcopenia

<p>Most patients with advanced cancer develop skeletal muscle atrophy called sarcopenia, which reduces treatment tolerance and social activity and worsens the prognosis. Glucose suppresses skeletal muscle atrophy in cancer-bearing mice, while promoting cancer growth. In contrast, medium-chain...

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Main Authors: Takuya Mori (Author), Akira Kido (Author), Isao Kawahara (Author), Shota Nuaga (Author), Yoshihiro Miyagawa (Author), Kei Goto (Author), Shiori Mori (Author), Shingo Kishi (Author), Kiyomu Fujii (Author), Rina Fujiwara-Tani (Author), Hiroki Kuniyasu (Author)
Format: Book
Published: Annals of Musculoskeletal Medicine - Peertechz Publications, 2021-01-06.
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042 |a dc 
100 1 0 |a Takuya Mori  |e author 
700 1 0 |a  Akira Kido  |e author 
700 1 0 |a  Isao Kawahara  |e author 
700 1 0 |a  Shota Nuaga  |e author 
700 1 0 |a  Yoshihiro Miyagawa  |e author 
700 1 0 |a  Kei Goto  |e author 
700 1 0 |a  Shiori Mori  |e author 
700 1 0 |a  Shingo Kishi  |e author 
700 1 0 |a  Kiyomu Fujii  |e author 
700 1 0 |a  Rina Fujiwara-Tani  |e author 
700 1 0 |a Hiroki Kuniyasu  |e author 
245 0 0 |a Nutritional intervention for cancer sarcopenia 
260 |b Annals of Musculoskeletal Medicine - Peertechz Publications,   |c 2021-01-06. 
520 |a <p>Most patients with advanced cancer develop skeletal muscle atrophy called sarcopenia, which reduces treatment tolerance and social activity and worsens the prognosis. Glucose suppresses skeletal muscle atrophy in cancer-bearing mice, while promoting cancer growth. In contrast, medium-chain fatty acids reduce skeletal muscle atrophy and suppress cancer growth. Simultaneous administration of glucose and medium-chain fatty acids suppresses skeletal muscle atrophy and eliminates the tumor growth seen in glucose. Based on these findings, dietary intervention using a combination of glucose and medium-chain fatty acids is expected to be effective in suppressing sarcopenia in cancer patients.</p> 
540 |a Copyright © Takuya Mori et al. 
546 |a en 
655 7 |a Research Article  |2 local 
856 4 1 |u https://doi.org/10.17352/amm.000024  |z Connect to this object online.