Cover Image

Recurrence of Immunotactoid Glomerulopathy with Monoclonal IgG3κ Deposits after Kidney Transplant

<p>We report a case of rapid recurrence of immunotactoid glomerulopathy (ITG) with monoclonal IgG3κ deposits in a transplanted renal graft. A 55-year-old hemodialysis male patient due to ITG underwent an ABO-incompatible living-donor kidney transplantation. Proteinuria (3.11 g/day) and increas...

Full description

Saved in:
Bibliographic Details
Main Authors: Katsuyuki Miki (Author), Maki Sumida (Author), Kazuhiro Iwadoh (Author), Kazuho Honda (Author), Toru Murakami (Author), Ichiro Koyama (Author), Ichiro Nakajima (Author), Shohei Fuchinoue (Author)
Format: Book
Published: Archives of Organ Transplantation - Peertechz Publications, 2017-06-30.
Subjects:
Case Report
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:<p>We report a case of rapid recurrence of immunotactoid glomerulopathy (ITG) with monoclonal IgG3κ deposits in a transplanted renal graft. A 55-year-old hemodialysis male patient due to ITG underwent an ABO-incompatible living-donor kidney transplantation. Proteinuria (3.11 g/day) and increased serum creatinine (2.52 mg/dL) were detected on postoperative day (POD) 4 due to acute antibody-mediated rejection (aAMR). Even after treatment for aAMR, proteinuria increased again to 4.5 g/day because of a recurrent ITG with IgG3κ subclass deposits. He returned to maintenance hemodialysis 9 months after transplantation. </p><p>This case underlines the importance of preoperative monoclonal paraproteinuria test to predict an ITG recurrence in the renal graft.</p>
DOI:10.17352/aot.000006

Similar Items