Mirabegron to manage symptoms of interstitial cystitis / bladder pain syndrome: A stone for two birds?

• Main Authors: João Antonio Pereira-Correia (Author), Luiza Amaral Nahoum (Author), João Ernesto Aldred Pinto (Author), Valter José Fernandes Muller (Author)
• Format: Book
• Published: Archive of Urological Research - Peertechz Publications, 2021-04-26.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Background: Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS) patients often experience lowered quality of life due to pain, urinary urgency, and increases in urinary frequency. Like many chronic pain disorders, IC/BPS is poorly understood and treatment unsatisfactory. </p><p>Materials and methods: We prospectively monitored the effects on pain and urinary complaints, of mirabegron associated with amitriptyline, for randomly selected women with IC/BPS. </p><p>Results: Twenty-five women were randomly selected to treat pain symptoms of IC/BPS and 12 followed up until the end of the study. All patients showed improvement on all questionnaires referring to pain IC/BPS symptoms and urinary storage symptoms. There was no statistically significant improvement in urinary frequency. </p><p>Conclusions: We suggest that mirabegron can work controlling urinary urgency and pain of IC/BPS patients.</p>