The Role of Decavanadate in Anti- Tumour Activity

<p>Decavanadate compounds were described to be involved in a variety of biological activities and responses such as anti-virus, anti-bacterial and anticancer. While the mechanisms of action of the antiviral and anti-bacterial activities are better understood, the same does not go for the anti-...

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Main Author: M Aureliano (Author)
Format: Book
Published: Global Journal of Cancer Therapy - Peertechz Publications, 2017-03-11.
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100 1 0 |a M Aureliano  |e author 
245 0 0 |a The Role of Decavanadate in Anti- Tumour Activity 
260 |b Global Journal of Cancer Therapy - Peertechz Publications,   |c 2017-03-11. 
520 |a <p>Decavanadate compounds were described to be involved in a variety of biological activities and responses such as anti-virus, anti-bacterial and anticancer. While the mechanisms of action of the antiviral and anti-bacterial activities are better understood, the same does not go for the anti-tumour activity. Nevertheless, the inhibition of tumour proliferation seems to impact certain enzymes such as alkaline phosphatase, ecto-nucleotidases or P-type ATPases. In the present report, several studies are described, in a way to explain the increasing interest of these polyoxometalate in cancer therapy. The detailed knowledge of the molecular basis of decavanadate-proteins and cellular interactions allows to better understand the processes associated with the anticancer applications, not only for decavanadate but as well for other polyoxometalates (POMs).</p> 
540 |a Copyright © M Aureliano et al. 
546 |a en 
655 7 |a Short Communication  |2 local 
856 4 1 |u https://doi.org/10.17352/gjct.000015  |z Connect to this object online.