Glutamic Acid Decarboxylase Autoantibodies Role in Reclassifying Diabetes of Adulthood in Basrah

<p><strong>Aim: </strong>To determine the prevalence and phenotypic characteristics of diabetes subtypes based on glutamic acid decarboxylase autoantibodies (GADA) status in those newly presented diabetic to the Al-Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC)...

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Main Authors: Abbas Ali Mansour (Author), Ammar Mohamd Saead Almomin (Author), Ali Hussein Ali Alhamza (Author)
Format: Book
Published: International Journal of Clinical Endocrinology and Metabolism - Peertechz Publications, 2015-07-15.
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Summary:<p><strong>Aim: </strong>To determine the prevalence and phenotypic characteristics of diabetes subtypes based on glutamic acid decarboxylase autoantibodies (GADA) status in those newly presented diabetic to the Al-Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah, Southern Iraq.</p><p><strong>Methods: </strong>The study design is cross-sectional and includes adult diabetic patients if they are free of insulin treatment for at least 6 months from diagnosis and to be 30 years of age and over from the period of January 2013 to March 2013.</p><p><strong>Results: </strong>Of our diabetics with age 30 years and more, 26.4% were GADA-positive. The only significantly higher variables seen more among GADA-positive diabetes groups were normal weight and current insulin uses. GADA-positivity was not associated with gender, age, BMI, family history, smoking, hypertension, duration of diabetes, or specific HbA1c in the current study.</p><p><strong>Conclusion: </strong>A quarter of adults diabetic in Basrah were GADA positive. GADA positivity means more likely to be normal weight diabetics and currently on insulin use.</p>
DOI:10.17352/ijcem.000004