An Analytical Study for Early Diagnosis and Treatment of Infants & Children Suffering From Congenital Hypothyroidism in China

• Main Authors: Fuyong Jiao (Author), Jianping Chen (Author), Juan Liu (Author), Ting Li (Author), Fangting Liu (Author)
• Format: Book
• Published: International Journal of Clinical Endocrinology and Metabolism - Peertechz Publications, 2015-07-15.
• Subjects: Case Report
• Online Access: Connect to this object online.

Summary

<p><strong>Objective:</strong> To study the clinical and laboratory characteristics of children suffering from congenital hypothyroidism in China.</p><p><strong>Method: </strong>455 cases of congenital hypothyroidism infants were collected from 5 articles were published in 4 china medical journals. Different screening methods were adopted, like enzyme immunoassay assay and filter paper dried blood biotin-avidin enzyme notation to test TSH, FT3、FT. All the collected children treated by oral thyroxin tablets for long period and regular follow-up was done. Clinical follow up for any signs of hypothyroidism and also detection of I.Q of those children.</p><p><strong>Results: </strong>Markedly effective group: IQ >70%, height, constipation, lethargy, abdominal distension, jaundice and other symptoms and signs were improved after treatment. Effective group: IQ: 30%-70%, height, constipation, lethargy, abdominal distension, jaundice and other symptoms and signs were improved after treatment. Poor effective group: 0-30% IQ, while other signs and symptoms not much improved. Laboratory testing revealed au thyroid along with oral treatment of thyroxin in regular time and dose.</p><p><strong>Conclusion: </strong>Congenital hypothyroidism is a preventable disease if early diagnosis and treatment was done.</p>

DOI

10.17352/ijcem.000005