In-silico analysis of tenidap and its derivative as a novel 5-lipoxygenase inhibitor
<p>Tenidap is a derivative of Flavonoids which are actually plant derivatives, it shows inhibition activity</p><p>of 5-lipoxygenase. Molecular models were directed to discover molecular docking mode, also to help</p><p>explain molecular tool behind its inhibitory action...
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International Journal of Pharmaceutical Sciences and Developmental Research - Peertechz Publications,
2017-11-24.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_ijpsdr_000015 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Asma Noor |e author |
| 700 | 1 | 0 | |a Ardas Masood |e author |
| 700 | 1 | 0 | |a Jawaria Khan |e author |
| 700 | 1 | 0 | |a Tanveer Abbas |e author |
| 700 | 1 | 0 | |a Muhammad Imran Qadir |e author |
| 245 | 0 | 0 | |a In-silico analysis of tenidap and its derivative as a novel 5-lipoxygenase inhibitor |
| 260 | |b International Journal of Pharmaceutical Sciences and Developmental Research - Peertechz Publications, |c 2017-11-24. | ||
| 520 | |a <p>Tenidap is a derivative of Flavonoids which are actually plant derivatives, it shows inhibition activity</p><p>of 5-lipoxygenase. Molecular models were directed to discover molecular docking mode, also to help</p><p>explain molecular tool behind its inhibitory action. Molecular relations of tenidap with the catalytic trio</p><p>(His523, His518, Ile875) inside active or dynamic position of 5-lipoxygenase through hydrogen bonding,</p><p>appears to the major reason elaborate in its substantial 5-lipoxygenase activity of inhibition.</p> | ||
| 540 | |a Copyright © Asma Noor et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Research Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/ijpsdr.000015 |z Connect to this object online. |