Spray dried self-nanoemulsifying drug delivery systems for sertraline HCl: Pharmacokinetic study in healthy volunteers

• Main Authors: Hussein O. Ammar (Author), Mahmoud M. Ghorab (Author), Dina M. Mostafa (Author), Amira M. Ghoneim (Author)
• Format: Book
• Published: International Journal of Pharmaceutical Sciences and Developmental Research - Peertechz Publications, 2018-06-27.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Purpose: The aim of this study is to improvelow oral bioavailability of sertraline HCl by formulation and characterization ofsolid self-nanoemulsifying drug delivery system [SNEDDS] using spray drying technique.</p><p>Methods: Solubility of sertraline HCl in different vehicles w...