Juvenile granulosa tumor of the ovary: Report of two cases

<p>Sex cord ovarian tumours are rare tumours that develop in non-germinal ovarian cells. The pathogenesis of these tumours remains undetermined and several cellular and molecular alterations may be involved in the development of juvenile granulosa cell tumours. The individualization of juvenil...

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Main Authors: Mohammed Lahfaoui (Author), Ahmed Azahouani (Author), Mohamed Belahcen (Author), Houssine Benhaddou (Author)
Format: Knjiga
Izdano: International Journal of Radiology and Radiation Oncology - Peertechz Publications, 2020-06-04.
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Izvleček:<p>Sex cord ovarian tumours are rare tumours that develop in non-germinal ovarian cells. The pathogenesis of these tumours remains undetermined and several cellular and molecular alterations may be involved in the development of juvenile granulosa cell tumours. The individualization of juvenile granulosa cell tumors has been a major advance in the treatment of these tumors in children over the past two decades. However, their natural history is reported in the literature and through a short and reliable series, prognostic factors have to be established. We report two cases of an 8 and 11 year old girl who presented with an abdomino-pelvic mass gradually increasing in size, on surgical exploration found a huge abdominal mass of the ovary. An anatomopathological study with immunostaining of the surgical specimen confirmed the diagnosis of a Juvenile granulosa cell ovarian tumor.</p>
DOI:10.17352/ijrro.000039