The association between copy number variant of Angiotensin Converting Enzyme gene and the risk of Ascending Aortic Aneurysm in Bicuspid and Tricuspid Aortic Valve
<p><strong>Introduction</strong>: The presence of ACE Insertion/Deletion polymorphism is proposed to be associated with a higher risk for abdominal aortic aneurysm. The aim of this study was to examine a relationship between the occurrence of I/D polymorphism among patients with as...
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Journal of Biology and Medicine - Peertechz Publications,
2019-08-20.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_jbm_000015 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Azadeh Motavalli Naeini |e author |
| 700 | 1 | 0 | |a Maryam Sotoudeh Anvari |e author |
| 700 | 1 | 0 | |a Shayan Ziaee |e author |
| 700 | 1 | 0 | |a Ali Hosseinsabet |e author |
| 700 | 1 | 0 | |a Mohammadali Boroumand |e author |
| 700 | 1 | 0 | |a Kyomars Abbasi |e author |
| 245 | 0 | 0 | |a The association between copy number variant of Angiotensin Converting Enzyme gene and the risk of Ascending Aortic Aneurysm in Bicuspid and Tricuspid Aortic Valve |
| 260 | |b Journal of Biology and Medicine - Peertechz Publications, |c 2019-08-20. | ||
| 520 | |a <p><strong>Introduction</strong>: The presence of ACE Insertion/Deletion polymorphism is proposed to be associated with a higher risk for abdominal aortic aneurysm. The aim of this study was to examine a relationship between the occurrence of I/D polymorphism among patients with ascending aortic aneurysm and bicuspid or tricuspid aortic valve structure.</p><p><strong>Material and method</strong>: In this case-control study, 360 patients divided into two groups: 1) patients with ascending aortic aneurysm and bicuspid or tricuspid aortic valve (n= 175), and 2) those without ascending aortic aneurysm as control samples (n=185). The presence of copy number variant (CNV) patterns (Insert/Deletion) of ACE gene was analyzed using real-time polymerase chain reaction.</p> | ||
| 540 | |a Copyright © Azadeh Motavalli Naeini et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Research Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/jbm.000015 |z Connect to this object online. |