Serum levels of Vitamin A and Atopic Rhinoconjunctivitis in Swedish adolescents
<p><strong>Aim</strong>: Vitamin A plays a role in mucosal immunity and tolerance, but the association between vitamin A status and allergy is still unclear. The aim of the study was to analyze the levels of vitamin A in serum from adolescents with or without atopic rhinoconjunctiv...
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Journal of Food Science and Nutrition Therapy - Peertechz Publications,
2017-09-12.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_jfsnt_000009 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Malin Barman |e author |
700 | 1 | 0 | |a Nils-Gunnar Carlsson |e author |
700 | 1 | 0 | |a Anna Sandin |e author |
700 | 1 | 0 | |a Agnes E. Wold |e author |
700 | 1 | 0 | |a Ann-Sofi e Sandberg |e author |
245 | 0 | 0 | |a Serum levels of Vitamin A and Atopic Rhinoconjunctivitis in Swedish adolescents |
260 | |b Journal of Food Science and Nutrition Therapy - Peertechz Publications, |c 2017-09-12. | ||
520 | |a <p><strong>Aim</strong>: Vitamin A plays a role in mucosal immunity and tolerance, but the association between vitamin A status and allergy is still unclear. The aim of the study was to analyze the levels of vitamin A in serum from adolescents with or without atopic rhinoconjunctivitis.</p><p><strong>Method</strong>: Thirteen-year-old children with atopic rhinoconjunctivitis (n = 53) and non-allergic, nonsensitized controls (n = 52) were randomly selected from a population based prospective birth cohort comprising 1228 children in Northern Sweden born in 1996-1997. Vitamin A (retinol) concentrations in serum were measured with high performance liquid chromatography mass spectrometry. Multiple logistic regression was used to evaluate the association between allergy prevalence and serum vitamin A levels.</p><p><strong>Results</strong>: Multiple logistic regression analysis showed no association between serum vitamin A levels and atopic rhinoconjunctivitis prevalence; OR = 1.00 (95% confidence interval 1.00-1.00), p = 0.81. Stratification for gender revealed a trend for a higher risk for having atopic rhinoconjunctivitis with higher concentrations of vitamin A in serum for females, OR = 1.02 (1.00-1.05), p = 0.07. No such associations were found in male subjects OR = 0.99 (0.97-1.01), p = 0.15. A dose-response relationship between allergy and vitamin A concentrations were also calculated but no such relationships were found, neither for all subjects nor for male and females separately.</p><p><strong>Conclusions</strong>: Serum levels of vitamin A could neither be positively nor negatively associated with atopic rhinoconjunctivitis in Swedish teenagers.</p> | ||
540 | |a Copyright © Malin Barman et al. | ||
546 | |a en | ||
655 | 7 | |a Research Article |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/jfsnt.000009 |z Connect to this object online. |