Evaluation of effi cacy & safety of oral fi xed dose combination of probiotics in bacterial vaginosis

• প্রধান লেখক: Arif Ahmed Faruqui (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Journal of Gynecological Research and Obstetrics - Peertechz Publications, 2019-08-02.
• বিষয়গুলি: Research Article
• অনলাইন ব্যবহার করুন: Connect to this object online.

<p><strong>Aim</strong>: To evaluate the effi cacy and safety of vaginal specifi c lactobacilli strain in management of bacterial vaginosis.</p><p><strong>Method</strong>: A non-randomized, open labeled, non-comparative, multi-centric, study was conducted in total of 58 female patients suffering from bacterial vaginosis. Each patient was administered a combination of four strains of Lactobacilli. Vaginal pH, discharge, odor, itching and painful urination were performed at baseline, week 2 and week 4 as assessment parameters.</p><p><strong>Result</strong>: At the end of study data was extractable in only 56 females (mean age was 34.57 ± 11 years). Associated BV symptoms like vaginal discharge, odor and painful urination reduced signifi cantly at week 4 as compared to baseline. The most frequently encountered symptom was vaginal discharge, vaginal pH, odor and itching. With a shift in pH<4.5, at the end of week 4 all females showed improvement in the vaginal microbiota. Tolerability of fi xed dose combination was found to be good and none of the subjects discontinued the treatment.</p>