Going Along the Direction of Trained Immunity - a Herbal Supplement for the Prevention of Respiratory Infection

<p>This is a report of a clinical attempt on the creation of an evidence-based herbal supplement for the personal protection against respiratory infection including COVID-19. The herbal supplement was derived from ancient Chinese herbal formulae. It had been proven safe and effective as a prev...

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Päätekijät: Ben CL Chan (Tekijä), Ping-Chung Leung (Tekijä), William KF Cheng (Tekijä), Zhixiu Lin (Tekijä), Edwin CL Yu (Tekijä), Ida MT Chu (Tekijä), Ping Chook (Tekijä), Carmen YS Fong (Tekijä), Chun-Kwok Wong (Tekijä)
Aineistotyyppi: Kirja
Julkaistu: Journal of Vaccines and Immunology - Peertechz Publications, 2020-11-10.
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042 |a dc 
100 1 0 |a Ben CL Chan  |e author 
700 1 0 |a  Ping-Chung Leung  |e author 
700 1 0 |a  William KF Cheng  |e author 
700 1 0 |a  Zhixiu Lin  |e author 
700 1 0 |a  Edwin CL Yu  |e author 
700 1 0 |a  Ida MT Chu  |e author 
700 1 0 |a  Ping Chook  |e author 
700 1 0 |a  Carmen YS Fong  |e author 
700 1 0 |a Chun-Kwok Wong  |e author 
245 0 0 |a Going Along the Direction of Trained Immunity - a Herbal Supplement for the Prevention of Respiratory Infection 
260 |b Journal of Vaccines and Immunology - Peertechz Publications,   |c 2020-11-10. 
520 |a <p>This is a report of a clinical attempt on the creation of an evidence-based herbal supplement for the personal protection against respiratory infection including COVID-19. The herbal supplement was derived from ancient Chinese herbal formulae. It had been proven safe and effective as a preventive agent during the 2003 SARS epidemic in Hong Kong. It was used again in this pandemic for the same purpose: offering extra personal protection for the frontline medical workers. While appreciations related to apparent preventive effects had been plentiful, a repetition of trial offered to a smaller group of 700 individuals was carried out. Apart from the need for the confirmation of safety and better quality of life, a subgroup of 33 volunteers offered to have their sera checked for immunological boosting effects as had been claimed. Results showed that the two weeks' herbal supplement did achieve a clear indication of boosted immunological defense via a macrophage orientated pathway as was indicated in the changes in chemokine activities. This effects could be understood as a demonstration of "trained immunity" process.</p> 
540 |a Copyright © Ben CL Chan et al. 
546 |a en 
655 7 |a Research Article  |2 local 
856 4 1 |u https://doi.org/10.17352/jvi.000035  |z Connect to this object online.