Potentiometric sensing platform for selective determination of Pregabalin in pharmaceutical formulations
<p>Pregabalin is a structural analogue of, but functionally unrelated to, the naturally occurring neurotransmitter -aminobutyric acid (GABA) with potent analgesic, anticonvulsant and anxiolytic activity. The abuse potential of pregabalin is a well-documented with high risk of addiction that m...
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Open Journal of Analytical and Bioanalytical Chemistry - Peertechz Publications,
2019-09-05.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_ojabc_000011 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Eman H El-Naby |e author |
| 245 | 0 | 0 | |a Potentiometric sensing platform for selective determination of Pregabalin in pharmaceutical formulations |
| 260 | |b Open Journal of Analytical and Bioanalytical Chemistry - Peertechz Publications, |c 2019-09-05. | ||
| 520 | |a <p>Pregabalin is a structural analogue of, but functionally unrelated to, the naturally occurring neurotransmitter -aminobutyric acid (GABA) with potent analgesic, anticonvulsant and anxiolytic activity. The abuse potential of pregabalin is a well-documented with high risk of addiction that may be fatal with overdoses particularly, among opiate addicts and polydrug use dependency syndrome, consequently, it is very pertinent to determine pregabalin in a sensitive and selective manner. Herein, for the fi rst time the use of β-cyclodextrin:phosphomolybdic acid organic-inorganic hybrid material as a neutral ionophore in polymeric membrane based selective sensors for the determination of pregabalin in its pharmaceutical formulations has been reported.</p> | ||
| 540 | |a Copyright © Eman H El-Naby et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Research Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/ojabc.000011 |z Connect to this object online. |