Development and validation of stability indicating RP-HPLC method for simultaneous estimation of Ibuprofen and Carisoprodol in Pharmaceutical formulation

<p>A novel, rapid, precise and accurate stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Ibuprofen and Carisoprodol in combined pharmaceutical formulation. Chromatographic separation was achieved on Kromasil C18 column (250×4.6mm, 5μm) with UV...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: A Lakshmana Rao (مؤلف), P Vijetha (مؤلف)
التنسيق: كتاب
منشور في: Open Journal of Analytical and Bioanalytical Chemistry - Peertechz Publications, 2019-11-06.
الموضوعات:
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الوسوم: إضافة وسم
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الوصف
الملخص:<p>A novel, rapid, precise and accurate stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Ibuprofen and Carisoprodol in combined pharmaceutical formulation. Chromatographic separation was achieved on Kromasil C18 column (250×4.6mm, 5μm) with UV detection at 260nm. The mobile phase consisting of 0.1% Ortho Phosphoric Acid (OPA) and acetonitrile in a ratio of 40:60v/v and adjusted the fl ow of mobile phase to 1.0mL/min.</p>
DOI:10.17352/ojabc.000014