Mechanism of multi-resistant bacterial pathogenesis: MDR genes are not so deadly unless plasmid-mediated toxin, virulence and regulatory genes are activated

• Main Authors: Kousik Poria (Author), Shampa Bhatta (Author), Sanatan Das (Author), Madhumita Dey (Author), Chandan Halder (Author), Sankalita Datta (Author), Asit Kumar Chakraborty (Author)
• Format: Book
• Published: Open Journal of Bacteriology - Peertechz Publications, 2020-04-04.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Mdr genes in association with many drug efflux and metal efflux genes are creating pathogenesis due to antibiotic void. However, most dangerous step occurred when R-plasmids and integrons (~2-9kb) were combined with F'-conjugative plasmid (62.5kb) creating large MDR conjugative plasmid...