Characteristics and outcome of fetal nuchal translucency above 3.5 mm in the fi rst trimester
<p><strong>Objective</strong>: To describe the natural history of fetuses with a nuchal translucency (NT) above 3.5 mm when crown-rump length measures between 45 and 84 mm.</p><p><strong>Methods</strong>: We performed a retrospective cohort study of fetuses...
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Open Journal of Biological Sciences - Peertechz Publications,
2019-07-22.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_ojbs_000013 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Cátia Lourenço |e author |
700 | 1 | 0 | |a Inês Gouveia |e author |
700 | 1 | 0 | |a Ana Carriço |e author |
700 | 1 | 0 | |a Francisco Valente |e author |
245 | 0 | 0 | |a Characteristics and outcome of fetal nuchal translucency above 3.5 mm in the fi rst trimester |
260 | |b Open Journal of Biological Sciences - Peertechz Publications, |c 2019-07-22. | ||
520 | |a <p><strong>Objective</strong>: To describe the natural history of fetuses with a nuchal translucency (NT) above 3.5 mm when crown-rump length measures between 45 and 84 mm.</p><p><strong>Methods</strong>: We performed a retrospective cohort study of fetuses with fi rst trimester NT above 3.5 mm between January 2013 and March 2017.</p><p><strong>Results</strong>: A total of 75 cases with NT above 3.5 mm in the fi rst trimester were identifi ed. 3 cases were excluded (lost to follow-up), so that 72 cases were included. There were additional fi rst trimester markers of aneuploidy in 16 cases and 5 cases of major structural abnormalities diagnosed in the fi rst trimester ultrasound. 2 cases declined invasive testing. The karyotype was abnormal in 30 cases (43%), including 17 cases of trisomy 21. There were 25 terminations of pregnancy (34.7%), 11 fetal deaths (15.3%) and 36 livebirths (50%). The 36 live-born infants were followed. In this group 3 cases of trisomy 21, 1 case of unilateral hypoplasia of orbicularis oris, 1 Noonan-like syndrome, 1 case of 8p23.1 duplication (benign variant) and 1 case of lower limb lymphedema were observed.</p> | ||
540 | |a Copyright © Cátia Lourenço et al. | ||
546 | |a en | ||
655 | 7 | |a Research Article |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/ojbs.000013 |z Connect to this object online. |