Evaluation of the toxicity of aqueous extracts of Aframomum melegueta, Picralima nitida, and Garcinia cola in Wistar rats

<p>In order to determine the risks to human health associated with the use of certain medicinal plants, including Aframomum melegueta, Garcinia kola and Picralima nitida in a preclinical evaluation of the resistance, a pool of these three aqueous extracts was given once daily for ten days by g...

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Asıl Yazarlar: Kabongo TJB (Yazar), Luvingisa LA (Yazar), Ngoie MP (Yazar), Musuyu MD (Yazar), Musunga MA (Yazar), Kabamba MW (Yazar), Pyana PP (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Open Journal of Biological Sciences - Peertechz Publications, 2023-05-11.
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042 |a dc 
100 1 0 |a Kabongo TJB  |e author 
700 1 0 |a  Luvingisa LA  |e author 
700 1 0 |a  Ngoie MP  |e author 
700 1 0 |a  Musuyu MD  |e author 
700 1 0 |a  Musunga MA  |e author 
700 1 0 |a  Kabamba MW  |e author 
700 1 0 |a Pyana PP  |e author 
245 0 0 |a Evaluation of the toxicity of aqueous extracts of Aframomum melegueta, Picralima nitida, and Garcinia cola in Wistar rats 
260 |b Open Journal of Biological Sciences - Peertechz Publications,   |c 2023-05-11. 
520 |a <p>In order to determine the risks to human health associated with the use of certain medicinal plants, including Aframomum melegueta, Garcinia kola and Picralima nitida in a preclinical evaluation of the resistance, a pool of these three aqueous extracts was given once daily for ten days by gavage in Wistar rats. Haematological and biochemical analyzes after oral administration revealed a decrease in certain hepatic biomarkers such as glucose, Alanine Aminotransferase (ALT), etc., and renal biomarkers such as urea, creatinine, and creatinine kinase); increase in certain biomarkers such as Aspartate Transaminase (AST), an indicator of kidney and liver capacity.</p> 
540 |a Copyright © Kabongo TJB et al. 
546 |a en 
655 7 |a Research Article  |2 local 
856 4 1 |u https://doi.org/10.17352/ojbs.000035  |z Connect to this object online.