Recent Structure Activity Relationship Studies of 1,4-Benzodiazepines
<p>Structure activity relationship studies of 1,4-benzodiazepines have been discussed especially with their effects as antianxiety and anticonvulsants. The currently available benzodiazepines are associated with various side effects. Nowadays the purpose of these studies is to minimize side ef...
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| Format: | Book |
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Open Journal of Chemistry - Peertechz Publications,
2015-11-10.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_ojc_000002 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Noor ul Amin Mohsin |e author |
| 700 | 1 | 0 | |a Muhammad Imran Qadir |e author |
| 245 | 0 | 0 | |a Recent Structure Activity Relationship Studies of 1,4-Benzodiazepines |
| 260 | |b Open Journal of Chemistry - Peertechz Publications, |c 2015-11-10. | ||
| 520 | |a <p>Structure activity relationship studies of 1,4-benzodiazepines have been discussed especially with their effects as antianxiety and anticonvulsants. The currently available benzodiazepines are associated with various side effects. Nowadays the purpose of these studies is to minimize side effects with these drugs. A very little alteration is possible on the benzene ring while the modification can be done on the diazepine ring. It can adopt the different conformations and in some cases some aromatic and heterocyclic rings have been fused with this part in order to see the effect of these conformation blockers on the pharmacological activity. The structure activity studies are also linked to molecular modeling studies. This is important in adding some information for the interaction of these drugs with the receptors and how this interaction can be improved.</p> | ||
| 540 | |a Copyright © Noor ul Amin Mohsin et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Review Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/ojc.000002 |z Connect to this object online. |