Lack of narrow therapeutic index awareness leading to increased risk of acute phenytoin toxicity in a child with traumatic brain injury
<p>Phenytoin is a commonly prescribed antiepileptic medication in the pediatric age group for multiple indications. It has a very narrow therapeutic range with well known side-effects. A careful dose dispensing is of utmost importance while administering medications with narrow therapeutic ind...
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| Main Authors: | , , |
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| Format: | Book |
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Open Journal of Pediatrics and Child Health - Peertechz Publications,
2021-04-10.
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| Online Access: | Connect to this object online. |
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| Summary: | <p>Phenytoin is a commonly prescribed antiepileptic medication in the pediatric age group for multiple indications. It has a very narrow therapeutic range with well known side-effects. A careful dose dispensing is of utmost importance while administering medications with narrow therapeutic index especially in pediatric age groups with variable weight bands. Multiple dosage formulations like tablets/syrups of varying strength ranging from 30-300mg are available in the market just with a small difference of color coding on the labels making it prone to iatrogenic errors leading to toxicity. </p> |
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| DOI: | 10.17352/ojpch.000032 |