To evaluate the anti-diabetic effects of Salvia cabulica ethanolic extract on alloxan-induced diabetic rabbits

<p>Objective: This study aimed to investigate the hypoglycemic effects of Salvia cabulica ethanolic extract on alloxan-induced diabetic rabbits. </p><p>Method: During the plant's extraction, the dried plant was soaked in ethanol for 14 days at room temperature and filtered. Th...

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Prif Awduron: Abdul Ghaffar (Awdur), Marvi (Awdur), Mohammad Younis (Awdur), Abdul Wahid (Awdur), Shafi Muhammad (Awdur), Faisal Ahmed (Awdur)
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Cyhoeddwyd: Open Journal of Pharmacology and Pharmacotherapeutics - Peertechz Publications, 2022-07-19.
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LEADER 00000 am a22000003u 4500
001 peertech__10_17352_ojpp_000020
042 |a dc 
100 1 0 |a Abdul Ghaffar  |e author 
700 1 0 |a  Marvi  |e author 
700 1 0 |a  Mohammad Younis  |e author 
700 1 0 |a  Abdul Wahid  |e author 
700 1 0 |a  Shafi Muhammad  |e author 
700 1 0 |a Faisal Ahmed  |e author 
245 0 0 |a To evaluate the anti-diabetic effects of Salvia cabulica ethanolic extract on alloxan-induced diabetic rabbits 
260 |b Open Journal of Pharmacology and Pharmacotherapeutics - Peertechz Publications,   |c 2022-07-19. 
520 |a <p>Objective: This study aimed to investigate the hypoglycemic effects of Salvia cabulica ethanolic extract on alloxan-induced diabetic rabbits. </p><p>Method: During the plant's extraction, the dried plant was soaked in ethanol for 14 days at room temperature and filtered. The dark green gummy filtrate was obtained by using a rotary evaporator at 40oC. Rabbits with fasting glucose levels of more than 250 mg/dL were considered diabetic. These rabbits were treated with aqueous plant extract in different doses (250 mg and 500 mg) respectively. </p><p>Results: The fasting blood glucose level (BGL) mean was 293 ± 25.65 in diabetic control group D-I compared to the normal control group A 99 ± 6.16 after the 48 hours of diabetes induction. The fasting blood glucose level (BGL) in group D-II was 192 ± 17.06, group D-III 93.515.95and group D-IV was 89.33 ± 7.79. </p><p>There was a significant decrease in blood glucose among the group III and IV treated with plant extract at 250 mg/kg and 500 mg/kg, respectively</p><p>Conclusion: The plant Salvia cabulica has potential hypoglycemic activity. Therefore, the medicinal plant can be used as a folklore herbal drug in the treatment of diabetes locally.</p> 
540 |a Copyright © Abdul Ghaffar et al. 
546 |a en 
655 7 |a Research Article  |2 local 
856 4 1 |u https://doi.org/10.17352/ojpp.000020  |z Connect to this object online.