Metals from cell to environment: Connecting Metallomics with other omics

• Autor principal: Vijeta Singhand Kusum Verma (Autor)
• Formato: Libro
• Publicado: Open Journal of Plant Science - Peertechz Publications, 2018-03-12.
• Materias: Review Article
• Acceso en línea: Connect to this object online.

<p>Research activities and data collection of metals present in living organisms are called as "metallomics".</p><p>In metallomics, biomolecules incorporating metal ions viz. metalloenzymes and metalloproteins, are</p><p>known as "metallomes". Metallomics aims to identify metallomes of living organisms and to annotate the</p><p>physiological signifi cance as well as the biological functions. However, in order to ascertain metallomics</p><p>to be the part of biometal science, recent analytical technologies like chemical speciation are required to</p><p>analyze the metallomes. Environmental applications like bioleaching, phytoremediation of soil by using</p><p>microbes, and to deal with the uptake, transport, storage of trace metals necessary for protein functions</p><p>and biomarkers identifi cation under ecotoxicological studies really require metallomics involvement. As</p><p>an interdisciplinary research area, metallomics cover plant and animal physiology, nutrition and become</p><p>a potential candidate in pharmacology, biogeochemistry and clinical chemistry. Metallomics uses</p><p>analytical and spectroscopic methods to fi nd the quantitative and qualitative information about metal</p><p>ions that are present as ligands a well multifaceted biological matrix in trace amounts or occur as noncovalent complexes in order to perform different biological processes. Latest spectroscopic methods</p><p>along with in-silico approaches including bioinformatics are the important tools needed for research</p><p>activities in metallomics. The present review highlights the basics of metallomics in biological sciences</p><p>and its emergence as a novel omics era in relation to other fi elds. Besides the above aspects, applications and future prospects of metallomics have been highlighted.</p>