Autoimmune Thyroid Diseases and Helicobacter Pylori

<p>Background: Helicobacter pylori infection is worldwide diffused with up to 50% of incidence in the population of the developed countries and the most virulent strains carrying the cytotoxin-associated gene A antigens. Moreover, bacterial and viral antigens have been suspected to be able to...

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Bibliographic Details
Main Authors: Vincenzo Bassi (Author), Olimpia Fattoruso (Author), Crescenzo Santinelli (Author)
Format: Book
Published: Open Journal of Thyroid Research - Peertechz Publications, 2017-01-02.
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042 |a dc 
100 1 0 |a Vincenzo Bassi  |e author 
700 1 0 |a  Olimpia Fattoruso  |e author 
700 1 0 |a Crescenzo Santinelli  |e author 
245 0 0 |a Autoimmune Thyroid Diseases and Helicobacter Pylori 
260 |b Open Journal of Thyroid Research - Peertechz Publications,   |c 2017-01-02. 
520 |a <p>Background: Helicobacter pylori infection is worldwide diffused with up to 50% of incidence in the population of the developed countries and the most virulent strains carrying the cytotoxin-associated gene A antigens. Moreover, bacterial and viral antigens have been suspected to be able to mimic the antigenic profile of the thyroid cell membrane suggesting an important role in the onset of the autoimmune diseases, such as Graves' disease and Hashimoto's thyroiditis. Aims: we reviewed the studies concerning the relationship between the bacterium and the autoimmune thyroid diseases such as Graves' and Hashimoto's disease. Conclusions: the significative association between Helicobacter pylori and Graves' disease suggests a possible role of this bacterium in the onset and/or the maintenance of the autoimmune disease.</p> 
540 |a Copyright © Vincenzo Bassi et al. 
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856 4 1 |u https://doi.org/10.17352/ojtr.000001  |z Connect to this object online.