Laryngeal Primary Amyloidosis: Differential Diagnosis of Localized Granulomatosis with Polyangiitis. Report of Two Cases

• Egile Nagusiak: Clarissa de Queiroz Pimentel (Egilea), Luciana Depiere Lanzarin (Egilea), Frederico Adão de Oliveira Santana (Egilea), Rosa Maria Rodrigues Pereira (Egilea), Maurício Levy-Neto (Egilea), Samuel Katsuyuki Shinjo (Egilea)
• Formatua: Liburua
• Argitaratua: Rheumatica Acta: Open Access - Peertechz Publications, 2017-03-08.
• Gaiak: Case Report
• Sarrera elektronikoa: Connect to this object online.

Gaia

<p>Primary laryngeal amyloidosis (PLA) and granulomatosis with polyangiitis (GPA) can present rarely with the isolated symptom of dyspnea and/or dysphonia, affecting exclusively the larynx. <br></p><p>Granulomatosis with polyangiitis is one of the anti-neutrophil cytoplasmatic antibodies (ANCA) associated vasculitis. It may be limited to the airways including may be exclusively laryngeal. This localized form of GPA has a diffi cult diagnosis because the biopsy rarely does the diagnosis and the ANCA tests are frequently negative.</p><p> In the aim of emphasizing the importance of this rare entity as a differential diag <br></p>

DOI

10.17352/raoa.000004