FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar

Flavonoids are used widely in the pharmaceutical industry due to their anti-oxidative and anti-inflammatory properties. However, most of the flavonoids are poorly water-soluble. These experiments were conducted to prepare the inclusion complex of β-Cyclodextrin with selected flavonoids such as Querc...

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Main Authors: Khosim, Noor Amilia (Author), Abdullah, Ainnie Rahayu (Author), Mokhtar, Marina (Author)
Format: Book
Published: Universiti Teknologi MARA, Pulau Pinang, 2015.
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LEADER 00000 am a22000003u 4500
001 repouitm_11993
042 |a dc 
100 1 0 |a Khosim, Noor Amilia  |e author 
700 1 0 |a Abdullah, Ainnie Rahayu  |e author 
700 1 0 |a Mokhtar, Marina  |e author 
245 0 0 |a FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar 
260 |b Universiti Teknologi MARA, Pulau Pinang,   |c 2015. 
500 |a https://ir.uitm.edu.my/id/eprint/11993/1/AJ_NOOR%20AMILIA%20KHOSIM%20EAJ%2015.pdf 
520 |a Flavonoids are used widely in the pharmaceutical industry due to their anti-oxidative and anti-inflammatory properties. However, most of the flavonoids are poorly water-soluble. These experiments were conducted to prepare the inclusion complex of β-Cyclodextrin with selected flavonoids such as Quercetin, Naringenin, 3-Hydroxyflavone and Chrysin. The methods used in complexing the host and guest molecules are modified physical mixture, kneading and freeze drying method by using the molar ratio of 1:1. The complexations of the flavonoids tested were analyzed by the Fourier Transform Infrared (FT-IR)spectroscopy. Analysis results suggested that the best method to complex β-Cyclodextrin with Quercetin and Chrysin, were via modified kneading method. Complexation of Naringenin and 3-Hydroxyflavone was best done via modified freeze drying and physical mixture method respectively. 
546 |a en 
690 |a RS Pharmacy and materia medica 
690 |a Pharmaceutical dosage forms 
655 7 |a Article  |2 local 
655 7 |a PeerReviewed  |2 local 
787 0 |n https://ir.uitm.edu.my/id/eprint/11993/ 
856 4 1 |u https://ir.uitm.edu.my/id/eprint/11993/  |z Link Metadata