Fabrication and characterization of flame retardant 4 and polydimethylsiloxane as substrates for a label-free DNA sensor / Irni Hamiza Hamzah, Emilia Noorsal, Mohammad Nizam Ibrahim, Asrulnizam Abd Manaf and Othman Sidek
Silicon, glass, and ceramic are commonly used base substrates for gold (Au) deposition on label-free DNA biosensors. This study aimed to investigate the suitability of applying flame retardant 4 (FR4) as a base substrate and polydimethylsiloxane (PDMS) as a coating substrate. A thermal evaporator wa...
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Universiti Teknologi MARA, Pulau Pinang & Pusat Penerbitan Universiti (UPENA),
2013.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | repouitm_8898 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Noorsal, Emilia |e author |
700 | 1 | 0 | |a Ibrahim, Mohammad Nizam |e author |
700 | 1 | 0 | |a Abd Manaf, Asrulnizam |e author |
245 | 0 | 0 | |a Fabrication and characterization of flame retardant 4 and polydimethylsiloxane as substrates for a label-free DNA sensor / Irni Hamiza Hamzah, Emilia Noorsal, Mohammad Nizam Ibrahim, Asrulnizam Abd Manaf and Othman Sidek |
260 | |b Universiti Teknologi MARA, Pulau Pinang & Pusat Penerbitan Universiti (UPENA), |c 2013. | ||
500 | |a https://ir.uitm.edu.my/id/eprint/8898/1/AJ_IRNI%20HAMIZA%20HAMZAH%20EAJ%2013.pdf | ||
520 | |a Silicon, glass, and ceramic are commonly used base substrates for gold (Au) deposition on label-free DNA biosensors. This study aimed to investigate the suitability of applying flame retardant 4 (FR4) as a base substrate and polydimethylsiloxane (PDMS) as a coating substrate. A thermal evaporator was used to fabricate copper/nickel/Au metals and ensure even deposition of Au throughout FR4. UV exposure soft lithography and wet etching were applied to develop a three-electrode pattern on the metals fabricated on FR4. A simple and straightforward technique on PDMS-FR4 bonding was proved to work at the shear strength of 55 kPa. A cyclic voltammetry (CV) method was performed using the fabricated FR4 sensor to analyze bare Au, DNA immobilization and hybridization. The FR4-based Au fabricated with PDMS acted as a coating layer between terminals and sensing electrodes, and can thus be used as a label-free DNA sensor. | ||
546 | |a en | ||
690 | |a TK Electrical engineering. Electronics. Nuclear engineering | ||
655 | 7 | |a Article |2 local | |
655 | 7 | |a NonPeerReviewed |2 local | |
787 | 0 | |n https://ir.uitm.edu.my/id/eprint/8898/ | |
856 | 4 | 1 | |u https://ir.uitm.edu.my/id/eprint/8898/ |z Link Metadata |