Pengaruh glutamin & glukosa unhidrat pada jumlah limfosit tikus model kurang energi protein

• Main Authors: Katmawanti, Septa (Author), Wirdjadmaji, Bambang (Author), Adi, Annis Catur (Author)
• Format: Book
• Published: 2016-06.
• Subjects: Article; PeerReviewed
• Online Access: Link Metadata
• Notes: http://repository.um.ac.id/927/1/7838-9562-1-SM.pdf
• Keywords: RA0421 Public health. Hygiene. Preventive Medicine; RS Pharmacy and materia medica

Protein-energy malnutrition condition causes lymphocytes number to decrease which then lead to body's cellular immune system disorders, the condition where patient is more vulnerable to infection. Number of lymphocytes in the body is dependent to some factors, some of them are anti-oxidant, amino acid glutamine and glucose. The aim of his research is to study the effect of L-glutamine and glucose unhidrate administration in rat model of protein-energy malnutrition to the increase of lymphocytes number in the blood. This is an experimental study with Completely Random Design. Sample is malnutrition induced with parched rice for 15 days (n=20). Then some samples are examined to figure out the lymphocytes number after the rate model experience lack of energy and protein. Sample is then divided into four treatment groups, they are: group with normal diet (control), normal diet + L-glutamine, normal diet + glucose unhidrate, and normal diet + L-glutamine + glucose unhidrate. Lymphocytes content is measured again after 10 days. The result of the study shows that number of lymphocytes increase significantly (P<0.05) in the four treatment groups after the intervention compared with number of lymphocytes in the malnutrition induced group. Statistical analysis of the four groups with L-glutamine and glucose unhidrate administered shows significant difference each other (p<0.05). These observations imply that the glutamin and gluocose unhidrat has an effect to the increase of lymphocytes number in the blood.