Uji Efek Analgetik Infusa Batang Brotowali (Tinospora Crispa (L.) Miers) Pada Mencit Putih Jantan Galur Swiss (Mus Musculus)

• Main Author: Chandra Septian, Prima (Author)
• Format: Book
• Published: 2016.
• Subjects: Thesis; NonPeerReviewed
• Online Access: Connect to this object online
• Notes: https://eprints.ums.ac.id/42364/1/10.%20NASKAH%20PUBLIKASI.pdf; https://eprints.ums.ac.id/42364/2/02.%20HALAMAN%20DEPAN.pdf; https://eprints.ums.ac.id/42364/3/03.%20BAB%201.pdf; https://eprints.ums.ac.id/42364/4/04.BAB%202.pdf; https://eprints.ums.ac.id/42364/5/05.%20BAB%203.pdf; https://eprints.ums.ac.id/42364/6/06.%20BAB%204.pdf; https://eprints.ums.ac.id/42364/7/07.%20BAB%205.pdf; https://eprints.ums.ac.id/42364/8/08.%20DAFTAR%20PUSTAKA.pdf; https://eprints.ums.ac.id/42364/9/09.%20LAMPIRAN.pdf; https://eprints.ums.ac.id/42364/10/01.%20SURAT%20PERNYATAAN%20PUBLIKASI%20KARYA%20ILMIAH.pdf
• Keywords: RM Therapeutics. Pharmacology

Background: Brotowali's stem (Tinospora crispa (L.) miers) has compounds alkaloid, soft damar, berberin, pati, glikosida pikroretosid, palmatin, bitter substance of pikoretin, harsa, flavonoid and tanin. Flavonoid compound has analgetic effect. Objective: To know the analgetic effect of brotowali's stem infused (Tinospora crispa (L.) miers)on swiss strain of male white mice (Mus musculus). Methods: It was an experimental laboratoric research using postest only with control group design. Animal under investigation was 30 swiss strain of male white mice (Mus musculus) divided into 5 treatment groups, they are group I aquadest negative control, group II positive control ibuprofen (1,04 mg/ kgBW), group III, IV, V: treated with brotowali's stem infused (Tinospora crispa (L.)miers) with the dosage of 7,8 %, 10,4%, 13% respectively. Result of Research: ANOVA test result obtained significant probability value p= 0.000 (p<0.05) it means in that from 5 groups there were two groups with significant difference. Conclusion: The results of this research showed brotowali's stem infused (Tinospora crispa (L.)miers) seeds with the dosage of 7,8 %, 10,4%, 13% had analgetic effect on swiss strain of male white mice (Mus musculus).