Uji Efek Hepatorepair Ekstrak Temulawak (Curcuma Xanthorrhiza Roxb) Pada Tikus Putih Jantan Galur Wistar Yang Diinduksi Paracetamol

Background: Temulawak (Curcuma xanthorrhiza Roxb) compounds curcumin, essential oil, glycosides, toluil, protein, and calium. Curcumin has the effect hepatorepair. This research use ginger rhizome. Ginger rhizome serves as hepatorepair. Objective: This study aimed to find out hepatorepair effect of...

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Main Authors: HADINATA, MUHAMMAD TEGUH (Author), , dr. Nurhayani M.Sc (Author), , dr. Rochmadina Suci Bestari M.Sc (Author)
Format: Book
Published: 2016.
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100 1 0 |a HADINATA, MUHAMMAD TEGUH  |e author 
700 1 0 |a , dr. Nurhayani M.Sc  |e author 
700 1 0 |a , dr. Rochmadina Suci Bestari M.Sc  |e author 
245 0 0 |a Uji Efek Hepatorepair Ekstrak Temulawak (Curcuma Xanthorrhiza Roxb) Pada Tikus Putih Jantan Galur Wistar Yang Diinduksi Paracetamol 
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500 |a https://eprints.ums.ac.id/42454/15/SURAT%20PERNYATAAN.pdf 
520 |a Background: Temulawak (Curcuma xanthorrhiza Roxb) compounds curcumin, essential oil, glycosides, toluil, protein, and calium. Curcumin has the effect hepatorepair. This research use ginger rhizome. Ginger rhizome serves as hepatorepair. Objective: This study aimed to find out hepatorepair effect of Temulawak (Curcuma xanthorrhiza Roxb) on male wistar strain rats induced by paracetamol. Methods: The method was experimental research with pre and postest control group design. Treatment group I was given distilled water (aquadest) as negative control, group II was given paracetamol as positive control, group III was given of ginger extract at a dose of 400 mg/kgBB, group IV was given of ginger extract at a dose of 800 mg/kgBB, group V was given of ginger extract at a dose of 1600 mg/kgBB. Result: ANNOVA test p value 0,000 for SGOT, and 0,002 for SGPT. It means that these two value <0,05 which can be interpreted to have the effect of ginger extract hepatorepair with the result obtained in the ANNOVA test. Conclusion: Ginger extract (Curcuma xanthorrhiza Roxb) had hepatorepair effect on male wistar strain rats induced by paracetamol. 
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