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UJI EFEK EKSTRAK ETANOL 70% AKAR KUMIS KUCING (Orthosiphon stamineus) TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH JANTAN GALUR WISTAR (Rattus norvegicus) YANG DIINDUKSI ALOKSAN

Orthosiphon stamineus contains flavonoid found on its leaves, roots, and flowers which has an effect to stimulate pancreas to produce insulin. To determine the effect of 70% ethanolic extract of Orthosiphon stamineus roots in decreasing blood glucose level of white male Wistar rats induced by alloxa...

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Bibliographic Details
Main Authors: SAPUTRI, MAHARANI EKA (Author), , DR. Dr. EM Sutrisna, M.Kes (Author)
Format: Book
Published: 2017.
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NonPeerReviewed
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Summary:Orthosiphon stamineus contains flavonoid found on its leaves, roots, and flowers which has an effect to stimulate pancreas to produce insulin. To determine the effect of 70% ethanolic extract of Orthosiphon stamineus roots in decreasing blood glucose level of white male Wistar rats induced by alloxan. It was an experimental study using pre and post-test with controlled group design method. The animals used were 25 white male Wistar rats divided into 5 treatment groups: 2 ml/200g distilled water (negative control), 0.126 mg/200g glibenclamide (positive control), with the doses of extract I 50 mg/200g, II 150 mg/200g, and III 250 mg/200g of body-weight this study was done for 14 days. Kruskall-Wallis test result showed p = 0.000 which means there was significant differences on blood glucose level reduction. The doses of 70% ethanolic extract of Orthosiphon stamineus roots I 50 mg/200g, II 150 mg/200g, and III 250 mg/200g. 70% ethanolic extract of Orthosiphon stamineus roots with the doses of I 50 mg/200g, II 150 mg/200g, and III 250 mg/200g of body-weight can reduce blood glucose level on Alloxan-induced white male rats Wistar. However, only the dose of 250 mg/200g of body-weight is almost as effective as glibenclamide administered for 14 days.
Item Description:https://eprints.ums.ac.id/50558/1/NASKAH%20PUBLIKASI.pdf
https://eprints.ums.ac.id/50558/2/HALAMAN%20DEPAN.pdf
https://eprints.ums.ac.id/50558/6/BAB%20I.pdf
https://eprints.ums.ac.id/50558/9/BAB%20II.pdf
https://eprints.ums.ac.id/50558/10/BAB%20III.pdf
https://eprints.ums.ac.id/50558/11/BAB%20IV.pdf
https://eprints.ums.ac.id/50558/16/BAB%20V.pdf
https://eprints.ums.ac.id/50558/17/DAFTAR%20PUSTAKA.pdf
https://eprints.ums.ac.id/50558/18/LAMPIRAN.pdf
https://eprints.ums.ac.id/50558/19/Surat%20Pernyataan%20Publikasi.pdf

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