Uji Efek Analgesik Virgin Coconut Oil (VCO) Pada Mencit Putih (Mus musculus) Jantan Galur Swiss

Background: VCO (Virgin Coconut Oil) is one of the processed coconut (Cocos nucifera L). Virgin coconut oil is often called as tropical oils because this palm plants common in tropical regions. VCO (Virgin Coconut Oil) are believed to have an analgesic effect because there is a lauric acid content w...

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Main Authors: Ramdhani Taniyo, Rifqi (Author), , dr. Devi Usdiana Rosyidah.,M.sc (Author)
Format: Book
Published: 2017-01-20.
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520 |a Background: VCO (Virgin Coconut Oil) is one of the processed coconut (Cocos nucifera L). Virgin coconut oil is often called as tropical oils because this palm plants common in tropical regions. VCO (Virgin Coconut Oil) are believed to have an analgesic effect because there is a lauric acid content which can modulate the proliferation of immune cells that can suppress pain. Research Objective: To determine the analgesic effect in VCO (Virgin Coconut Oil). Research Method: The method used in the study Analgesic Effect Test VCO is by post test only with controlled group design. Test animals used were 25 male albino swiss mice (Mus musculus) and divided into five treatment groups: group I: as a negative control group, treated by distilled water, group II: as a control positive group, treated by Ibuprofen at a dose of 450mg / kg, group III: as the first treatment group, treated by VCO with dose of 0,15 ml , group IV: as the second treatment group, treated by VCO with dose of 0,3 ml, group V: as the third treatment group, treated by VCO with dose of 0,3 ml. Result of Research: Based on the Anova statistical test obtained by value p = 0.000 thus p < 0.05 means VCO (Virgin Coconut Oil) has an analgesic effect. Result of post hoc test showed negative between the groups (II) and the treatment group (III, IV, V) values; 0,000; 0.000; 0.000 (p < 0.05) 
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