EFEK IMUNOMODULATOR MADU (HONEY BEE) DAN ROYAL JELLY TERHADAP SISTEM IMUN KASUS COVID-19 : Systematic Review
COVID-19 causes millions of cases and thousands of deaths worldwide. Transmission of SARS-CoV-2 infection causes varied clinical symptoms. COVID-19 is closely related to the body's immunity which has an involved role in treatment, especially using herbal plants. Previous research on alternative...
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2022-01-17.
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| 245 | 0 | 0 | |a EFEK IMUNOMODULATOR MADU (HONEY BEE) DAN ROYAL JELLY TERHADAP SISTEM IMUN KASUS COVID-19 : Systematic Review |
| 260 | |c 2022-01-17. | ||
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| 520 | |a COVID-19 causes millions of cases and thousands of deaths worldwide. Transmission of SARS-CoV-2 infection causes varied clinical symptoms. COVID-19 is closely related to the body's immunity which has an involved role in treatment, especially using herbal plants. Previous research on alternative medicine has proven the effectiveness of honey and royal jelly products, many of which come from Indonesian natural forest bees. Honey bee products prove a protective immune system response from flavonoid compounds as antiviral and immunomodulators containing royal jelly MRJP and 10-HDA. Both are proven by comprehensively accurate data which have the same effect on immunomodulators in cases of COVID-19. Method: Systematic Literature Review with literature search strategy using PubMed, Google Scholar, ProQuest, and Science Direct. The literature used discusses Honey (Honey Bee), Royal Jelly, immunomodulatory effects and the immune system. Results: 7 research articles described evidence of honey and royal jelly as immunomodulatory effects on the immune system of COVID-19 cases in the moderate, strong, and very strong categories. Conclusion: Honey and royal jelly have the potential to provide an immunomodulatory effect because honey contains flavonoids while in royal jelly is MRJPs and 10-HDA there is an Ig-G and Ig-M antibody response in humoral cells while cellular cells are T cell presentation of lymphocytes, macrophages, neutrophils and inflammatory mediators such as cytokines IL-4,IL-1, IL-6 and TNF and NK cells. | ||
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