PENGARUH PENGGUNAAN ANTIKOAGULAN TERHADAP MORTALITAS PASIEN COVID-19 DENGAN RISIKO KOAGULOPATI: Systematic Review
Background: One of the most common cause of death in hospitalized COVID-19 patients is related with the progression of coagulopathy that caused by hyperinflammatory events thus causing a systemic cytokine storm resulting systemic inflammatory response syndrome (SIRS). In COVID-19 guideline of treatm...
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| Format: | Book |
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2022-01-10.
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| Summary: | Background: One of the most common cause of death in hospitalized COVID-19 patients is related with the progression of coagulopathy that caused by hyperinflammatory events thus causing a systemic cytokine storm resulting systemic inflammatory response syndrome (SIRS). In COVID-19 guideline of treatment by Indonesian Association of Pulmonary, Cardiovascular, and Internal Medicine Physicians recommends the use of anticoagulants in all hospitalized COVID-19 patient adjusted with appropriate clinical judgement. This systematic review was conducted to analyze the effect of anticoagulants use on mortality in COVID-19 patients who at risk of coagulopathy. Methods: A systematic review conducted by starting a literature search from May to July 2021. The literature that being analyzed was from Google Scholar, PubMed, EBSCO, and Science Direct database using PRISMA-P 2020. Results: Datas were obtained from nine journals. Eight of them stated that the use of prophylactic and therapeutic doses, has an effect on reducing the mortality rate of COVID-19 patients and one journal did not see a significant difference on mortality of COVID-19 patients. Types of anticoagulant that are widely used in nine journals are heparin and fondaparinux with doses adjusted to coagulation marker. Conclusion:The use of anticoagulant is beneficial in reducing mortality rates in hospitalized COVID-19 patients. |
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| Item Description: | http://repository.upnvj.ac.id/16307/1/ABSTRAK.pdf http://repository.upnvj.ac.id/16307/15/AWAL.pdf http://repository.upnvj.ac.id/16307/3/BAB%201.pdf http://repository.upnvj.ac.id/16307/5/BAB%202.pdf http://repository.upnvj.ac.id/16307/6/BAB%203.pdf http://repository.upnvj.ac.id/16307/7/BAB%204.pdf http://repository.upnvj.ac.id/16307/8/BAB%205.pdf http://repository.upnvj.ac.id/16307/9/DAFTAR%20PUSTAKA.pdf http://repository.upnvj.ac.id/16307/11/DAFTAR%20RIWAYAT%20HIDUP.pdf http://repository.upnvj.ac.id/16307/12/LAMPIRAN.pdf http://repository.upnvj.ac.id/16307/14/Hasil%20Plagiarisme.pdf http://repository.upnvj.ac.id/16307/13/ARTIKEL%20KI.pdf |