Search Results - "CRISPR"

The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events by Josephine M. Janssen, Xiaoyu Chen, Jin Liu, Manuel A.F.V. Gonçalves

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CRISPR Start-Loss: A Novel and Practical Alternative for Gene Silencing through Base-Editing-Induced Start Codon Mutations by Siyu Chen, Wanhua Xie, Zhiquan Liu, Huanhuan Shan, Mao Chen, Yuning Song, Hao Yu, Liangxue Lai, Zhanjun Li

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Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation by Anna-Lena Panagiotopoulos, Nina Karguth, Marina Pavlou, Sybille Böhm, Gilles Gasparoni, Jörn Walter, Alexander Graf, Helmut Blum, Martin Biel, Lisa Maria Riedmayr, Elvir Becirovic

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CRISPR/Cas9-Directed Reassignment of the GATA1 Initiation Codon in K562 Cells to Recapitulate AML in Down Syndrome by Kevin M. Bloh, Pawel A. Bialk, Anilkumar Gopalakrishnapillai, E. Anders Kolb, Eric B. Kmiec

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CRISPR/Cas9-mediated correction of MITF homozygous point mutation in a Waardenburg syndrome 2A pig model by Jing Yao, Yu Wang, Chunwei Cao, Ruigao Song, Dengfeng Bi, Hongyong Zhang, Yongshun Li, Guosong Qin, Naipeng Hou, Nan Zhang, Jin Zhang, Weiwei Guo, Shiming Yang, Yanfang Wang, Jianguo Zhao

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TREX2 enables efficient genome disruption mediated by paired CRISPR-Cas9 nickases that generate 3'-overhanging ends by Yue Wang, Yi-Li Feng, Qian Liu, Jing-Jing Xiao, Si-Cheng Liu, Zhi-Cheng Huang, An-Yong Xie

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A humanized knockin mouse model of Duchenne muscular dystrophy and its correction by CRISPR-Cas9 therapeutic gene editing by Yu Zhang, Hui Li, Takahiko Nishiyama, John R. McAnally, Efrain Sanchez-Ortiz, Jian Huang, Pradeep P.A. Mammen, Rhonda Bassel-Duby, Eric N. Olson

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CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model by Freja K. Ekman, David S. Ojala, Maroof M. Adil, Paola A. Lopez, David V. Schaffer, Thomas Gaj

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Poly(Beta-Amino Ester) Nanoparticles Enable Nonviral Delivery of CRISPR-Cas9 Plasmids for Gene Knockout and Gene Deletion by Yuan Rui, Mahita Varanasi, Shanelle Mendes, Hannah M. Yamagata, David R. Wilson, Jordan J. Green

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Allele-Specific CRISPR/Cas9 Correction of a Heterozygous DNM2 Mutation Rescues Centronuclear Myopathy Cell Phenotypes by Aymen Rabai, Léa Reisser, Bernardo Reina-, Kamel Mamchaoui, Belinda S. Cowling, Anne-Sophie Nicot, Jocelyn Laporte

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CRISPR-Cas9 knockout of membrane-bound alkaline phosphatase or cadherin does not confer resistance to Cry toxins in Aedes aegypti. by Sabino Pacheco, Adrián S Gallegos, Ángel E Peláez-Aguilar, Jorge Sánchez, Isabel Gómez, Mario Soberón, Alejandra Bravo

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Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion by Liu Yang, Margret A. Fye, Bingyuan Yang, Zihan Tang, Yue Zhang, Sander Haigh, Brittney A. Covington, Kai Bracey, Justin W. Taraska, Irina Kaverina, Shen Qu, Wenbiao Chen

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Broad-spectrum gRNAs abolish HIV-1 LTR-mediated transcription in cells that receive CRISPR/Cas9 therapy by B. Wigdahl, A. Allen, S. Worell, G. Nwaozo, R. Madrid, W. Dampier, M. Nonnemacher

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A global comprehensive study of the distribution of type I-E and type I-E* CRISPR-Cas systems in Klebsiella pneumoniae by Anand Babu Kannadasan, Venil Naranan Sumantran, Rama Vaidyanathan

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Engineered Adipose-Derived Stem Cells Overexpressing RXFP1 via CRISPR Activation Ameliorate Erectile Dysfunction in Diabetic Rats by Taotao Sun, Wenchao Xu, Bocheng Tu, Tao Wang, Jihong Liu, Kang Liu, Yang Luan

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PP 4.22 - 00087 Reversal of exhaustion of HIV-1-specific CTLs by CRISPR-mediated disruption of PD-1 gene by C. Baez, S. Brancazio, L. Shan, T. Burdo, R. Kaminski

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CRISPR knockdown of Kcnq3 attenuates the M-current and increases excitability of NPY/AgRP neurons to alter energy balance by Todd L. Stincic, Martha A. Bosch, Avery C. Hunker, Barbara Juarez, Ashley M. Connors, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly

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Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy by Alba García-Fernández, Gema Vivo-Llorca, Mónica Sancho, Alicia Belén García-Jareño, Laura Ramírez-Jiménez, Eloísa Barber-Cano, José Ramón Murguía, Mar Orzáez, Félix Sancenón, Ramón Martínez-Máñez

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A dual conditional CRISPR-Cas9 system to activate gene editing and reduce off-target effects in human stem cells by Seung Bum Park, Takuro Uchida, Samantha Tilson, Zongyi Hu, Christopher D. Ma, Madeleine Leek, Michael Eichner, So Gun Hong, T. Jake Liang

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A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition by Srinivasan Chinnapaiyan, Maria-Jose Santiago, Kingshuk Panda, Md. Sohanur Rahman, Jessica Alluin, John Rossi, Hoshang J. Unwalla

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