Search Results - "CRISPR"

miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways by Guoshu Bi, Jiaqi Liang, Mengnan Zhao, Huan Zhang, Xing Jin, Tao Lu, Yuansheng Zheng, Yunyi Bian, Zhencong Chen, Yiwei Huang, Valeria Besskaya, Cheng Zhan, Qun Wang, Lijie Tan

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Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis by Tamara Heintze, Tamara Heintze, Denise Wilhelm, Thierry Schmidlin, Thierry Schmidlin, Thierry Schmidlin, Ute Hofmann, Ute Hofmann, Ulrich M. Zanger, Ulrich M. Zanger, Matthias Schwab, Matthias Schwab, Matthias Schwab, Kathrin Klein, Kathrin Klein

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NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch by Séan M. O'Cathail, Chieh-Hsi Wu, Rachael Thomas, Maria A. Hawkins, Tim S. Maughan, Annabelle Lewis

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Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects by Gist H. Farr, Kimia Imani, Darren Pouv, Lisa Maves

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In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods by Sowmya Pattabhi, Samantha N. Lotti, Mason P. Berger, Swati Singh, Christopher T. Lux, Kyle Jacoby, Calvin Lee, Olivier Negre, Andrew M. Scharenberg, David J. Rawlings

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Cadmium chloride down-regulates the expression of Rad51 in HC11 cells and reduces knock-in efficiency by Ga-Yeon Kim, Man-Jong Kang

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Aedes cadherin receptor that mediates Bacillus thuringiensis Cry11A toxicity is essential for mosquito development. by Jianwu Chen, Karly G Aimanova, Sarjeet S Gill

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Syntaxin-17-Dependent Mitochondrial Dynamics is Essential for Protection Against Oxidative-Stress-Induced Apoptosis by Binran Wang, Xiaoyue Xiao, Fanwei Huang, Rong Liu

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CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons by S. Schuster, E. Heuten, A. Velic, J. Admard, M. Synofzik, S. Ossowski, B. Macek, S. Hauser, L. Schöls

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Pro-Resolving FPR2 Agonists Regulate NADPH Oxidase-Dependent Phosphorylation of HSP27, OSR1, and MARCKS and Activation of the Respective Upstream Kinases by Rosario Ammendola, Melania Parisi, Gabriella Esposito, Fabio Cattaneo

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Methicillin Resistance Elements in the Canine Pathogen <i>Staphylococcus pseudintermedius</i> and Their Association with the Peptide Toxin PSM-mec by Gordon Y. C. Cheung, Ji Hyun Lee, Ryan Liu, Sara D. Lawhon, Ching Yang, Michael Otto

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Editorial: Antimicrobial Resistance as a Global Public Health Problem: How Can We Address It? by Luciene Andrade Da Rocha Minarini, Leonardo Neves de Andrade, Eliana De Gregorio, Filipa Grosso, Thierry Naas, Raffaele Zarrilli, Ilana L. B. C. Camargo

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Activated PI3K delta syndrome 1 mutations cause neutrophilia in zebrafish larvae by Stone Elworthy, Holly A. Rutherford, Tomasz K. Prajsnar, Noémie M. Hamilton, Katja Vogt, Stephen A. Renshaw, Alison M. Condliffe

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Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids by Jinlun Bai, David S. Koos, Kayla Stepanian, Zachary Fouladian, Dominic W. H. Shayler, Jennifer G. Aparicio, Scott E. Fraser, Rex A. Moats, David Cobrinik

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PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis by Max J. van Essen, Elizabeth J. Apsley, Joey Riepsaame, Ruijie Xu, Paul A. Northcott, Sally A. Cowley, John Jacob, Esther B. E. Becker

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Stem cell modeling of nervous system tumors by Frank B. Furnari, Corina Anastasaki, Shan Bian, Howard A. Fine, Tomoyuki Koga, Lu Q. Le, Fausto J. Rodriguez, David H. Gutmann

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Loss of zebrafish pkd1l1 causes biliary defects that have implications for biliary atresia splenic malformation by Rouknuddin Q. Ali, Anne Meyer-Miner, Marie David-Rachel, Fiona J. H. Lee, Benjamin J. Wilkins, Saul J. Karpen, Brian Ciruna, Anand Ghanekar, Binita M. Kamath

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Genetic perturbations go spatial by Katie Teng, Hartland Warren Jackson

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ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality by Elena Sindram, Andrés Caballero-Oteyza, Naoko Kogata, Shaina Chor Mei Huang, Zahra Alizadeh, Laura Gámez-Díaz, Mohammad Reza Fazlollhi, Xiao Peng, Bodo Grimbacher, Michael Way, Michele Proietti

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Human induced-T-to-natural killer cells have potent anti-tumour activities by Zhiwu Jiang, Le Qin, Yuou Tang, Rui Liao, Jingxuan Shi, Bingjia He, Shanglin Li, Diwei Zheng, Yuanbin Cui, Qiting Wu, Youguo Long, Yao Yao, Zhihui Wei, Qilan Hong, Yi Wu, Yuanbang Mai, Shixue Gou, Xiaoping Li, Robert Weinkove, Sam Norton, Wei Luo, Weineng Feng, Hongsheng Zhou, Qifa Liu, Jiekai Chen, Liangxue Lai, Xinwen Chen, Duanqing Pei, Thomas Graf, Xingguo Liu, Yangqiu Li, Pentao Liu, Zhenfeng Zhang, Peng Li

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