Search Results - "CRISPR"

Pluripotency-State-Dependent Role of Dax1 in Embryonic Stem Cells Self-Renewal by Jianrong He, Yuda Cheng, Yan Ruan, Jiali Wang, Yanping Tian, Jiaqi Wang, Fengsheng Wang, Chen Zhang, Yixiao Xu, Lianlian Liu, Meng Yu, Jiangjun Wang, Binyu Zhao, Yue Zhang, Yi Yang, Gaoke Liu, Wei Wu, Ping He, Jiaxiang Xiong, He Huang, Junlei Zhang, Rui Jian

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Secreted PGK1 and IGFBP2 contribute to the bystander effect of miR-10b gene editing in glioma by Yanhong Zhang, Rosalia Rabinovsky, Zhiyun Wei, Rachid El Fatimy, Evgeny Deforzh, Bai Luan, Leonid Peshkin, Erik J. Uhlmann, Anna M. Krichevsky

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Gene Editing in Pluripotent Stem Cells and Their Derived Organoids by Hang Zhou, Yun Wang, Li-Ping Liu, Yu-Mei Li, Yun-Wen Zheng

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Editing of homologous globin genes by nickase-deficient base editor mitigates large intergenic deletions in HSPCs by Anila George, Poornasree Sadanandan, Nithin Sam Ravi, B. Vaishnavi, Srujan Marepally, Saravanbhavan Thangavel, Shaji R. Velayudhan, Alok Srivastava, Kumarasamypet M Mohankumar

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Diversity of International High-Risk Clones of <i>Acinetobacter baumannii</i> Revealed in a Russian Multidisciplinary Medical Center during 2017-2019 by Andrey Shelenkov, Lyudmila Petrova, Mikhail Zamyatin, Yulia Mikhaylova, Vasiliy Akimkin

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The Anti-Aging Hormone Klotho Promotes Retinal Pigment Epithelium Cell Viability and Metabolism by Activating the AMPK/PGC-1α Pathway by Shuyan Zhou, Jacob Hum, Kaan Taskintuna, Stephanie Olaya, Jeremy Steinman, Junfeng Ma, Nady Golestaneh

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Knockout of c‐Cbl slows EGFR endocytic trafficking and enhances EGFR signaling despite incompletely blocking receptor ubiquitylation by Brandon L. M. Crotchett, Brian P. Ceresa

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Lung Cancer Management with Silibinin: A Historical and Translational Perspective by Sara Verdura, Elisabet Cuyàs, Verónica Ruiz-Torres, Vicente Micol, Jorge Joven, Joaquim Bosch-Barrera, Javier A. Menendez

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Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells by Rina Hashimoto, Ayaka Sakamoto, Sayaka Deguchi, Renxing Yi, Emi Sano, Akitsu Hotta, Kazutoshi Takahashi, Shinya Yamanaka, Kazuo Takayama

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Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside Epidermis by Céline Evrard, Emilie Faway, Evelyne De Vuyst, Olivier Svensek, Valérie De Glas, David Bergerat, Michel Salmon, Olivier De Backer, Bruno Flamion, Hélène Le-Buanec, Catherine Lambert de Rouvroit, Yves Poumay

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lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway by Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

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Multi-component Chinese medicine formulas for drug discovery: State of the art and future perspectives by Cheng Zhang, Guoming Chen, Guoyi Tang, Xiaoyu Xu, Zixin Feng, Yuanjun Lu, Yau-Tuen Chan, Junyu Wu, Yuanyuan Chen, Lin Xu, Qing Ren, Hongchao Yuan, Dong-Hua Yang, Zhe-Sheng Chen, Ning Wang, Yibin Feng

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Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells by Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, Silvia Blacher, Laurent Massotte, Emmannuel Di Valentin, Denis Furling, Nicolas Albert Gillet, Arnaud François Klein, Vincent Seutin, Luc Willems

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Integrating Ligand-Receptor Interactions and In Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands by Hasan E. Zumrut, Sana Batool, Kimon V. Argyropoulos, Nicole Williams, Roksana Azad, Prabodhika R. Mallikaratchy

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The olfactory receptor OR51E2 activates ERK1/2 through the Golgi-localized Gβγ-PI3Kγ-ARF1 pathway in prostate cancer cells by Xin Xu, Mostafa Khater, Guangyu Wu

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Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy by Zekun Li, Yongchun Pan, Shiyu Du, Yayao Li, Chao Chen, Hongxiu Song, Yueyao Wu, Xiaowei Luan, Qin Xu, Xiaoxiang Guan, Yujun Song, Xin Han

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Carbon-based nanomaterials in gene therapy by Ebrahim Mostafavi, Hossein Zare

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Role and mechanism of NCAPD3 in promoting malignant behaviors in gastric cancer by Su-Yun Zhang, Qiong Luo, Li-Rong Xiao, Fan Yang, Jian Zhu, Xiang-Qi Chen, Xiang-Qi Chen, Sheng Yang, Sheng Yang

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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin by Francisco Javier García-Rodríguez, Carmen Martínez-Fernández, David Brena, Dmytro Kukhtar, Xènia Serrat, Ernest Nadal, Mike Boxem, Sebastian Honnen, Antonio Miranda-Vizuete, Alberto Villanueva, Julián Cerón

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Ku80 is involved in telomere maintenance but dispensable for genomic stability in Leishmania mexicana. by Ester Poláková, Amanda T S Albanaz, Alexandra Zakharova, Tatiana S Novozhilova, Evgeny S Gerasimov, Vyacheslav Yurchenko

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