Search Results - "CRISPR"

Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice by Benjamin E. Low, Gregory J. Christianson, Emily Lowell, Wenning Qin, Michael V. Wiles

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PTK2 is a potential biomarker and therapeutic target for EGFR- or TLRs-induced lung cancer progression via the regulation of the cross-talk between EGFR- and TLRs-mediated signals by Ji Young Kim, Ji Hye Shin, Mi-Jeong Kim, Bongkum Choi, Yeeun Kang, Jimin Choi, Seo Hyun Kim, Dohee Kwan, Duk-Hwan Kim, Eunyoung Chun, Ki-Young Lee

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PPARγ Transcription Deficiency Exacerbates High-Fat Diet-Induced Adipocyte Hypertrophy and Insulin Resistance in Mice by Fusheng Guo, Shuangshuang Xu, Yanlin Zhu, Xing Zheng, Yi Lu, Jui Tu, Ying He, Lihua Jin, Lihua Jin, Yong Li

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Engineering death resistance in CHO cells for improved perfusion culture by Michael A. MacDonald, Matthias Nöbel, Verónica S. Martínez, Kym Baker, Evan Shave, Peter P. Gray, Stephen Mahler, Trent Munro, Lars K. Nielsen, Esteban Marcellin

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Rapid detection of myeloid neoplasm fusions using single-molecule long-read sequencing. by Olga Sala-Torra, Shishir Reddy, Ling-Hong Hung, Lan Beppu, David Wu, Jerald Radich, Ka Yee Yeung, Cecilia C S Yeung

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Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids by Emily L. Miedzybrodzka, Rachel E. Foreman, Van B. Lu, Amy L. George, Christopher A. Smith, Pierre Larraufie, Richard G. Kay, Deborah A. Goldspink, Frank Reimann, Fiona M. Gribble

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Opportunities, challenges and future perspectives of using bioinformatics and artificial intelligence techniques on tropical disease identification using omics data by S. M. Vidanagamachchi, K. M. G. T. R. Waidyarathna

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CVM-1118 (foslinanib), a 2-phenyl-4-quinolone derivative, promotes apoptosis and inhibits vasculogenic mimicry via targeting TRAP1 by Lifen Shen, Yen-Ling Chen, Chu-Chun Huang, Yu-Chiau Shyu, Yu-Chiau Shyu, Richard E. B. Seftor, Elisabeth A. Seftor, Mary J. C. Hendrix, Du-Shieng Chien, Yi-Wen Chu

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Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus by Dmitry Kostyushev, Sergey Brezgin, Anastasiya Kostyusheva, Natalia Ponomareva, Ekaterina Bayurova, Natalia Zakirova, Alla Kondrashova, Irina Goptar, Anastasiya Nikiforova, Anna Sudina, Yurii Babin, Ilya Gordeychuk, Alexander Lukashev, Andrey A. Zamyatnin, Jr, Alexander Ivanov, Vladimir Chulanov

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The bloodstream form of Trypanosoma brucei displays non-canonical gluconeogenesis. by Julie Kovářová, Martin Moos, Michael P Barrett, David Horn, Alena Zíková

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Targeting the IGF1R Pathway in Breast Cancer Using Antisense lncRNA-Mediated Promoter cis Competition by Lingling Pian, Xue Wen, Lihua Kang, Zhaozhi Li, Yuanyuan Nie, Zhonghua Du, Dehai Yu, Lei Zhou, Lin Jia, Naifei Chen, Dan Li, Songling Zhang, Wei Li, Andrew R. Hoffman, Jingnan Sun, Jiuwei Cui, Ji-Fan Hu

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Monocarboxylate Transporter 6-Mediated Interactions with Prostaglandin F_2α: In Vitro and In Vivo Evidence Utilizing a Knockout Mouse Model by Robert S. Jones, Mark D. Parker, and Marilyn E. Morris

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Pharmacological inhibition of BAP1 recruits HERC2 to competitively dissociate BRCA1-BARD1, suppresses DNA repair and sensitizes CRC to radiotherapy by Xin Yue, Tingyu Liu, Xuecen Wang, Weijian Wu, Gesi Wen, Yang Yi, Jiaxin Wu, Ziyang Wang, Weixiang Zhan, Ruirui Wu, Yuan Meng, Zhirui Cao, Liyuan Le, Wenyan Qiu, Xiaoyue Zhang, Zhenyu Li, Yong Chen, Guohui Wan, Xianzhang Bu, Zhenwei Peng, Ran-yi Liu

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Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain by Laura E. Kuil, Nynke Oosterhof, Samuël N. Geurts, Herma C. van der Linde, Erik Meijering, Tjakko J. van Ham

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Disruption of multiple copies of the Prostaglandin F2alpha synthase gene affects oxidative stress response and infectivity in Trypanosoma cruzi. by Ana Maria Murta Santi, Juliana Martins Ribeiro, João Luís Reis-Cunha, Gabriela de Assis Burle-Caldas, Isabella Fernandes Martins Santos, Paula Alves Silva, Daniela de Melo Resende, Daniella Castanheira Bartholomeu, Santuza Maria Ribeiro Teixeira, Silvane Maria Fonseca Murta

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NCAPG Is a Promising Therapeutic Target Across Different Tumor Types by Cuicui Xiao, Jiao Gong, Yusheng Jie, Jing Cao, Zhongcheng Chen, Rong Li, Yutian Chong, Bo Hu, Qi Zhang

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Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway by Yiqi Li, Yeli Li, Nana Chen, Linying Feng, Jianmei Gao, Nan Zeng, Zhixu He, Qihai Gong

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C3orf70 Is Involved in Neural and Neurobehavioral Development by Yoshifumi Ashikawa, Takashi Shiromizu, Koki Miura, Yuka Adachi, Takaaki Matsui, Yasumasa Bessho, Toshio Tanaka, Yuhei Nishimura

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Regenerative Medicine, Disease Modelling, and Drug Discovery in Human Pluripotent Stem Cell-Derived Kidney Tissue by Navin Gupta, Koichiro Susa, Ryuji Morizane

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Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model by William M. Parkinson, Michelle Dookwah, Mary Lynn Dear, Cheryl L. Gatto, Kazuhiro Aoki, Michael Tiemeyer, Kendal Broadie

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