অনুসন্ধান ফলাফলগুলি - "CRISPR"

Targeting the T-type calcium channel Cav3.2 in GABAergic arcuate nucleus neurons to treat obesity অনুযায়ী Bing Feng, Jerney Harms, Nirali Patel, Hui Ye, Pei Luo, Valeria Torres Irizarry, Jacob Vidrine, Ann Coulter, Candida J. Rebello, Sangho Yu, Jia Fan, Hans-Rudolf Berthoud, Frank Greenway, Heike Münzberg, Christopher Morrison, Pingwen Xu, Yanlin He

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Germline PRDM1 Variant rs2185379 in Long-Term Recurrence-Free Survivors of Advanced Ovarian Cancer অনুযায়ী Mitamura T, Zhai T, Hatanaka KC, Hatanaka Y, Amano T, Wang L, Tanaka S, Watari H

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Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension অনুযায়ী Yuhei eNishimura, Shota eSasagawa, Hirofumi eSawada, Erquan eZhang, Soichiro eMurakami, Yoshifumi eAshikawa, Mizuki eYuge, Shiko eOkabe, Koki eKawaguchi, Reiko eKawase, Yoshihide eMitani, Kazuo eMaruyama, TOSHIO eTANAKA

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Long‐noncoding RNA Atrolnc‐1 promotes muscle wasting in mice with chronic kidney disease অনুযায়ী Lijing Sun, Meijun Si, Xinyan Liu, Jong Min Choi, Yanlin Wang, Sandhya S. Thomas, Hui Peng, Zhaoyong Hu

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What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira. অনুযায়ী Derrick E Fouts, Michael A Matthias, Haritha Adhikarla, Ben Adler, Luciane Amorim-Santos, Douglas E Berg, Dieter Bulach, Alejandro Buschiazzo, Yung-Fu Chang, Renee L Galloway, David A Haake, Daniel H Haft, Rudy Hartskeerl, Albert I Ko, Paul N Levett, James Matsunaga, Ariel E Mechaly, Jonathan M Monk, Ana L T Nascimento, Karen E Nelson, Bernhard Palsson, Sharon J Peacock, Mathieu Picardeau, Jessica N Ricaldi, Janjira Thaipandungpanit, Elsio A Wunder, X Frank Yang, Jun-Jie Zhang, Joseph M Vinetz

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Antisense RNA Design, Delivery, and Analysis

সূচিপত্রের সারণি: “…Introduction and History of the Chemistry of Nucleic Acids Therapeutics -- Antisense RNA Therapeutics: A Brief Overview -- Design of Bifunctional Antisense Oligonucleotides for Exon Inclusion -- Design and Delivery of SINEUP: A New Modular Tool to Increase Protein Translation -- How to Design U1 snRNA Molecules for Splicing Rescue -- Conjugation of Nucleic Acids and Drugs to Gold Nanoparticles -- Determination of Optimum Ratio of Cationic Polymers and Small Interfering RNA with Agarose Gel Retardation Assay -- Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen -- Development and Use of Cellular Systems to Assess and Correct Splicing Defects -- Modeling Splicing Variants Amenable to Antisense Therapy by Use of CRISPR-Cas9-Based Gene Editing in HepG2 Cells -- In Vitro Models for the Evaluation of Antisense Oligonucleotides in Skin -- In Vitro Delivery of PMOs in Myoblasts by Electroporation -- Rapid Determination of MBNL1 Protein Levels by Quantitative Dot Blot for Evaluation of Antisense Oligonucleotides in Myotonic Dystrophy Myoblasts -- Evaluation of Exon Skipping and Dystrophin Restoration in In Vitro Models of Duchenne Muscular Dystrophy -- Generation of Human iPSC-Derived Myotubes to Investigate RNA-Based Therapies In Vitro -- Eye on a Dish Models to Evaluate Splicing Modulation -- Establishment of In Vitro Brain Models for AON Delivery -- Considerations for Generating Humanized Mouse Models to Test Efficacy of Antisense Oligonucleotides -- Generation of Humanized Zebrafish Models for the In Vivo Assessment of Antisense Oligonucleotide-Based Splice Modulation Therapies -- Use of Small Animal Models for Duchenne and Parameters to Assess Efficiency upon Antisense Treatment -- In Vivo Models for the Evaluation of Antisense Oligonucleotides in Skin -- Delivery of Antisense Oligonucleotides to the Mouse Retina -- Delivery of Antisense Oligonucleotides to the Mouse Brain by Intracerebroventricular Injections -- Intrathecal Delivery of Therapeutic Oligonucleotides for Potent Modulation of Gene Expression in the Central Nervous System -- Preclinical Safety Assessment of Therapeutic Oligonucleotides -- Preclinical Evaluation of the Renal Toxicity of Oligonucleotide Therapeutics in Mice -- Protocol for Isolation and Culture of Mouse Hepatocytes (HCs), Kupffer Cells (KCs), and Liver Sinusoidal Endothelial Cells (LSECs) in Analyses of Hepatic Drug Distribution -- Patent Considerations When Embarking on New Antisense Drug Programs.…”
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Emerging Approaches for Typing, Detection, Characterization, and Traceback of Escherichia coli অনুযায়ী David S. Needleman

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Emerging Approaches for Typing, Detection, Characterization, and Traceback of Escherichia coli, 2nd Edition অনুযায়ী David S. Needleman

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Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy অনুযায়ী Mina Shahriyari, Md Rezaul Islam, Sadman M. Sakib, Malte Rinn, Anastasia Rika, Dennis Krüger, Lalit Kaurani, Verena Gisa, Mandy Winterhoff, Harithaa Anandakumar, Orr Shomroni, Matthias Schmidt, Gabriela Salinas, Andreas Unger, Wolfgang A. Linke, Jana Zschüntzsch, Jens Schmidt, Rhonda Bassel‐Duby, Eric N. Olson, André Fischer, Wolfram‐Hubertus Zimmermann, Malte Tiburcy

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S100A9 as a Key Myocardial Injury Factor Interacting with ATP5 Exacerbates Mitochondrial Dysfunction and Oxidative Stress in Sepsis-Induced Cardiomyopathy অনুযায়ী Pei H, Qu J, Chen J, Zhao G, Lu Z

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Neurogranin as an important regulator in swimming training to improve the spatial memory dysfunction of mice with chronic cerebral hypoperfusion অনুযায়ী Huawei Lin, Jiayong Zhang, Yaling Dai, Huanhuan Liu, Xiaojun He, Lewen Chen, Jing Tao, Chaohui Li, Weilin Liu

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Hepatic Activin E mediates liver-adipose inter-organ communication, suppressing adipose lipolysis in response to elevated serum fatty acids অনুযায়ী John D. Griffin, Joanne M. Buxton, Jeffrey A. Culver, Robert Barnes, Emily A. Jordan, Alexis R. White, Stephen E. Flaherty, Barbara Bernardo, Trenton Ross, Kendra K. Bence, Morris J. Birnbaum

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LPS-Induced Activation of the cGAS-STING Pathway is Regulated by Mitochondrial Dysfunction and Mitochondrial DNA Leakage in Endometritis অনুযায়ী Li M, Wen X, Liu X, Wang Y, Yan L

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Diversity and Evolution of Butterfly Wing Patterns An Integrative Approach /

সূচিপত্রের সারণি: “…Developmental Genetics -- Chapter8:A practical guide to CRISPR/Cas9 genome editing in Lepidoptera -- Chapter9:What can we learn about adaptation from the wing pattern genetics of Heliconiusbutterflies? …”
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EmbryoGenetics

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Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia অনুযায়ী Isabella Pototschnig, Ursula Feiler, Clemens Diwoky, Paul W. Vesely, Thomas Rauchenwald, Margret Paar, Latifa Bakiri, Laura Pajed, Peter Hofer, Karl Kashofer, Nyamdelger Sukhbaatar, Gabriele Schoiswohl, Thomas Weichhart, Gerald Hoefler, Christoph Bock, Martin Pichler, Erwin F. Wagner, Rudolf Zechner, Martina Schweiger

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The X‐linked Becker muscular dystrophy (bmx) mouse models Becker muscular dystrophy via deletion of murine dystrophin exons 45-47 অনুযায়ী Christopher R. Heier, Nikki M. McCormack, Christopher B. Tully, James S. Novak, Breanne L. Newell‐Stamper, Alan J. Russell, Alyson A. Fiorillo

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The p97‐Nploc4 ATPase complex plays a role in muscle atrophy during cancer and amyotrophic lateral sclerosis অনুযায়ী Andrea David Re Cecconi, Mara Barone, Simona Gaspari, Massimo Tortarolo, Caterina Bendotti, Luca Porcu, Giulia Terribile, Rosanna Piccirillo

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Plant Disease Management in the Post-Genomic Era: from Functional Genomics to Genome Editing

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Interactions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis অনুযায়ী Wang H, Wang R, Yang J, Feng Y, Xu S, Pei QG

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