Search Results - "Genome editing"

Rationally designed Campylobacter jejuni Cas9 enables efficient gene activation and base editing by Yuxi Chen, Rui Kang, Yuanling Jiang, Qi Zheng, Yue Yang, Jiaqi Liu, Guanglan Wu, Weijun Zhao, Zhan Li, Chengxiang Peng, Pengfei Zhang, Fei Peng, Qianyi Liu, Sihui Hu, Xiao Luo, Guifang Wu, Kaixin Cui, Junjiu Huang, Yongming Wang, Zhou Songyang, Puping Liang

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CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development by Gokul Kesavan, Avinash Chekuru, Anja Machate, Michael Brand

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Genetic mapping in crop plants by Temesgen Begna, Husen Yesuf

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Evolution of Organismal Form: From Regulatory Interactions to Developmental Processes and Biological Patterns by Sylvain Marcellini

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CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease by Bence György, Camilla Lööv, Mikołaj P. Zaborowski, Shuko Takeda, Benjamin P. Kleinstiver, Caitlin Commins, Ksenia Kastanenka, Dakai Mu, Adrienn Volak, Vilmantas Giedraitis, Lars Lannfelt, Casey A. Maguire, J. Keith Joung, Bradley T. Hyman, Xandra O. Breakefield, Martin Ingelsson

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The E3 Ubiquitin Ligase Gene <i>Sl1</i> Is Critical for Cadmium Tolerance in <i>Solanum lycopersicum</i> L. by Chen-Xu Liu, Ting Yang, Hui Zhou, Golam Jalal Ahammed, Zhen-Yu Qi, Jie Zhou

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CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse by Xiao-Rui Luan, Xiao-Ling Chen, Yue-Xiao Tang, Jin-Yan Zhang, Xiang Gao, Hai-Ping Ke, Zhao-Yu Lin, Xian-Ning Zhang

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CRISPR-mediated optogene expression from a cell-specific endogenous promoter in retinal ON-bipolar cells to restore vision by A. Maddalena, A. Maddalena, S. Kleinlogel, S. Kleinlogel, S. Kleinlogel

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Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout by Yvonne Knopp, Franziska K. Geis, Dirk Heckl, Stefan Horn, Thomas Neumann, Johannes Kuehle, Janine Meyer, Boris Fehse, Christopher Baum, Michael Morgan, Johann Meyer, Axel Schambach, Melanie Galla

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A rapid and effective method for screening, sequencing and reporter verification of engineered frameshift mutations in zebrafish by Sergey V. Prykhozhij, Shelby L. Steele, Babak Razaghi, Jason N. Berman

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Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing by Qianying Zhao, Qiuhong Qian, Dongyan Cao, Jiaxin Yang, Ting Gui, Keng Shen

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Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies? by Lucia La Sala, Valentina Carlini, Caterina Conte, Maria Belen Macas-Granizo, Elham Afzalpour, Jimmy Martin-Delgado, Marco D'Anzeo, Roberto F.E. Pedretti, Angelo Naselli, Antonio E. Pontiroli, Riccardo Cappato

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Inborn errors of immunity-recent advances in research on the pathogenesis by Motoi Yamashita, Kento Inoue, Tsubasa Okano, Tomohiro Morio

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A non-viral and selection-free COL7A1 HDR approach with improved safety profile for dystrophic epidermolysis bullosa by Thomas Kocher, Johannes Bischof, Simone Alexandra Haas, Oliver Patrick March, Bernadette Liemberger, Stefan Hainzl, Julia Illmer, Anna Hoog, Katharina Muigg, Heide-Marie Binder, Alfred Klausegger, Dirk Strunk, Johann Wolfgang Bauer, Toni Cathomen, Ulrich Koller

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Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells by Carina Lund, Venkatram Yellapragada, Sanna Vuoristo, Diego Balboa, Sara Trova, Cecile Allet, Nazli Eskici, Kristiina Pulli, Paolo Giacobini, Timo Tuuri, Taneli Raivio

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CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncerta... by Troy A. McDiarmid, Vinci Au, Aaron D. Loewen, Joseph Liang, Kota Mizumoto, Donald G. Moerman, Catharine H. Rankin

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Stat3 Regulates Developmental Hematopoiesis and Impacts Myeloid Cell Function via Canonical and Non-Canonical Modalities by Mohamed Luban Sobah, Clifford Liongue, Alister C. Ward

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Human induced pluripotent stem cells technology in treatment resistant depression: novel strategies and opportunities to unravel ketamine's fast-acting antidepressant mechanisms by Matteo Marcatili, Carlo Sala, Antonios Dakanalis, Fabrizia Colmegna, Armando D'Agostino, Orsola Gambini, Bernardo Dell'Osso, Beatrice Benatti, Luciano Conti, Massimo Clerici

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Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish by Yonghe Ding, Alexey V. Dvornikov, Xiao Ma, Hong Zhang, Yong Wang, Matthew Lowerison, Rene R. Packard, Lei Wang, Jun Chen, Yuji Zhang, Tzung Hsiai, Xueying Lin, Xiaolei Xu

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A quantitative systems pharmacology (QSP) platform for preclinical to clinical translation of in-vivo CRISPR-Cas therapy by Devam A. Desai, Stephan Schmidt, Rodrigo Cristofoletti

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